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Relationship between Red Cell Deformability and Shear Stress in Conditions of Low Shear Rate in Vascular Dementia

Piotr Kowal
Renata Modestowicw

Puni tekst: engleski, pdf (47 KB) str. 211-211 preuzimanja: 373* citiraj
APA 6th Edition
Kowal, P. i Modestowicw, R. (2002). Relationship between Red Cell Deformability and Shear Stress in Conditions of Low Shear Rate in Vascular Dementia. Acta clinica Croatica, 41 (3), 211-211. Preuzeto s https://hrcak.srce.hr/14734
MLA 8th Edition
Kowal, Piotr i Renata Modestowicw. "Relationship between Red Cell Deformability and Shear Stress in Conditions of Low Shear Rate in Vascular Dementia." Acta clinica Croatica, vol. 41, br. 3, 2002, str. 211-211. https://hrcak.srce.hr/14734. Citirano 17.11.2019.
Chicago 17th Edition
Kowal, Piotr i Renata Modestowicw. "Relationship between Red Cell Deformability and Shear Stress in Conditions of Low Shear Rate in Vascular Dementia." Acta clinica Croatica 41, br. 3 (2002): 211-211. https://hrcak.srce.hr/14734
Harvard
Kowal, P., i Modestowicw, R. (2002). 'Relationship between Red Cell Deformability and Shear Stress in Conditions of Low Shear Rate in Vascular Dementia', Acta clinica Croatica, 41(3), str. 211-211. Preuzeto s: https://hrcak.srce.hr/14734 (Datum pristupa: 17.11.2019.)
Vancouver
Kowal P, Modestowicw R. Relationship between Red Cell Deformability and Shear Stress in Conditions of Low Shear Rate in Vascular Dementia. Acta clinica Croatica [Internet]. 2002 [pristupljeno 17.11.2019.];41(3):211-211. Dostupno na: https://hrcak.srce.hr/14734
IEEE
P. Kowal i R. Modestowicw, "Relationship between Red Cell Deformability and Shear Stress in Conditions of Low Shear Rate in Vascular Dementia", Acta clinica Croatica, vol.41, br. 3, str. 211-211, 2002. [Online]. Dostupno na: https://hrcak.srce.hr/14734. [Citirano: 17.11.2019.]

Sažetak
The aim of the study was to evaluate the effect of shear stress connected with low shear rate on red blood cell deformability in chronic brain ischemia. The study was carried out in a group of 18 patients with vascular dementia and control group of ten healthy subjects. Shear stress was calculated as a function of blood viscosity and basic shear stress for the applied range of shear rate. Red cell deformability (red cell transit time, RCTT) was investigated by filtration method, and the level of fibrinogen was assessed by use of a Chromotimer device. Then the relationship of particular shear stress with RCTT and fibrinogen was analyzed. In comparison to the control group, patients with vascular dementia showed higher levels of RCTT (p<0.05) and fibrinogen (p<0.01). Statistically significant correlations between RCTT and shear stress at a shear rate of 3.23 s-1 (p<0.02) and 0.695 s-1 (p<0.05) were found in the group of patients with vascular dementia. Results of the study suggested that in the group of patients with vascular dementia, shear stress in the range of low shear rate considerably affected the RBC membrane, thus contributing to impairment of its elasticity.

Ključne riječi
Dementia - physiology; Cerebrovascular disorders - blood; Blood viscosity - physiology; Erythrocyte deformability - physiology

Hrčak ID: 14734

URI
https://hrcak.srce.hr/14734

[hrvatski]

Posjeta: 768 *