Paediatria Croatica, Vol. 59 No. 3, 2015.
Izvorni znanstveni članak
https://doi.org/10.13112/PC.2015.22
The prevalence of hypertension and cardiovascular risks in children with renal scars secondary to urinary tract infection
Nakysa Hooman
orcid.org/0000-0002-8494-947X
; Iran University of Medical Sceinces, Tehran, Iran
Roya Isa-Tafreshi
Seyed-Hassan Mostafavi
Farideh Halladji
Azita Tavasoli
Minoo Saeidy
Mitra Mehrazma
Hasan Otukesh
Sažetak
Hypertension is a late outcome of refl ux nephropathy and renal parenchymal scar secondary to urinary tract infection (UTI). We
presumed that it might be detected much earlier after episodes of UTI and the associated cardiovascular risk factors assessed.
Between 2009 and 2011, 85 (67 female and 18 male) children aged 5-15 years with a history of febrile UTI, followed-up for at least
one year from the fi rst episode of febrile UTI, were enrolled in the study. The variables included 24-hour ambulatory blood pressure
monitoring (ABPM), echocardiography, carotid sonography, renal 99mcTc-DMSA, glomerular fi ltration rate, and microalbuminuria.
Masked hypertension was detected in 18.8%, hypertension in 7.1% and white coat hypertension in 9.4% of cases. Prehypertension
was seen in 20% of children. Out of 85 cases, 43.5% were non-dippers. Out of 56 children with hypertensive and prehypertensive
parameters on ABPM, 9.1% showed left ventricular mass index >51g/m2.7 (p>0.05). Signifi cant correlation was only recorded
between abnormal blood pressure and the severity of renal parenchymal scar (p<0.05). In conclusion, ABPM is suggested for early
detection of masked hypertension and abnormal blood pressure pattern in all normotensive children with a history of recurrent UTI.
Ključne riječi
blood pressure monitoring, ambulatory; urinary tract infections; hypertrophy, left ventricular; carotid intima-media thickness; early diagnosis
Hrčak ID:
153102
URI
Datum izdavanja:
25.9.2015.
Posjeta: 1.383 *