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Acta clinica Croatica, Vol. 54. No. 4., 2015.

Izvorni znanstveni članak

Glioblastoma multiforme brain tumors located in the motor cortex - specific findings in comparison with low grade gliomas of the same localization: analysis of a sixty patient series

Miodrag Stojsavljević ; Clinical Department of Neurosurgery, Clinical Center of Serbia, Belgrade, Serbia
Goran Tasić ; School of Medicine, University of Belgrade, Serbia
Igor Nikolić ; Clinical Department of Neurosurgery, Clinical Center of Serbia, Belgrade, Serbia
Nikola Repac ; Clinical Department of Neurosurgery, Clinical Center of Serbia, Belgrade, Serbia
Aleksandar Janićijević ; Clinical Department of Neurosurgery, Clinical Center of Serbia, Belgrade, Serbia
Vuk Šćepanović ; Clinical Department of Neurosurgery, Clinical Center of Serbia, Belgrade, Serbia
Krešimir Rotim ; Clinical Department of Neurosurgery, Clinical Center of Serbia, Belgrade, Serbia
Lukas Rasulić ; Clinical Department of Neurosurgery, Clinical Center of Serbia, Belgrade, Serbia; School of Medicine, University of Belgrade, Serbia

Puni tekst: engleski, pdf (146 KB) str. 402-408 preuzimanja: 322* citiraj
APA 6th Edition
Stojsavljević, M., Tasić, G., Nikolić, I., Repac, N., Janićijević, A., Šćepanović, V., ... Rasulić, L. (2015). Glioblastoma multiforme brain tumors located in the motor cortex - specific findings in comparison with low grade gliomas of the same localization: analysis of a sixty patient series. Acta clinica Croatica, 54. (4.), 402-408. Preuzeto s https://hrcak.srce.hr/154823
MLA 8th Edition
Stojsavljević, Miodrag, et al. "Glioblastoma multiforme brain tumors located in the motor cortex - specific findings in comparison with low grade gliomas of the same localization: analysis of a sixty patient series." Acta clinica Croatica, vol. 54., br. 4., 2015, str. 402-408. https://hrcak.srce.hr/154823. Citirano 19.02.2019.
Chicago 17th Edition
Stojsavljević, Miodrag, Goran Tasić, Igor Nikolić, Nikola Repac, Aleksandar Janićijević, Vuk Šćepanović, Krešimir Rotim i Lukas Rasulić. "Glioblastoma multiforme brain tumors located in the motor cortex - specific findings in comparison with low grade gliomas of the same localization: analysis of a sixty patient series." Acta clinica Croatica 54., br. 4. (2015): 402-408. https://hrcak.srce.hr/154823
Harvard
Stojsavljević, M., et al. (2015). 'Glioblastoma multiforme brain tumors located in the motor cortex - specific findings in comparison with low grade gliomas of the same localization: analysis of a sixty patient series', Acta clinica Croatica, 54.(4.), str. 402-408. Preuzeto s: https://hrcak.srce.hr/154823 (Datum pristupa: 19.02.2019.)
Vancouver
Stojsavljević M, Tasić G, Nikolić I, Repac N, Janićijević A, Šćepanović V i sur. Glioblastoma multiforme brain tumors located in the motor cortex - specific findings in comparison with low grade gliomas of the same localization: analysis of a sixty patient series. Acta clinica Croatica [Internet]. 2015 [pristupljeno 19.02.2019.];54.(4.):402-408. Dostupno na: https://hrcak.srce.hr/154823
IEEE
M. Stojsavljević, et al., "Glioblastoma multiforme brain tumors located in the motor cortex - specific findings in comparison with low grade gliomas of the same localization: analysis of a sixty patient series", Acta clinica Croatica, vol.54., br. 4., str. 402-408, 2015. [Online]. Dostupno na: https://hrcak.srce.hr/154823. [Citirano: 19.02.2019.]

Sažetak
The verified presence of a glioblastoma multiforme (GBM ) tumor in the motor area of the brain, in a patient lacking preoperative neurological deficit, offers no certainty that the tumor can be radically removed without the possibility of causing postoperative motor deficit. We present a series of 60 patients hospitalized at the Clinical Department of Neurosurgery, Clinical Center of Serbia in Belgrade between October 2011 and February 2015, harboring tumors located
within and in the vicinity of the motor zone of the brain. By using Karnofsky‘s index (KI), the pre- and postoperative conditions of the patients were evaluated. Regarding electrical stimulation of the motor cortex, significantly lower values of the electrical current intensity, frequency, and pulse wave duration (p<0.01) were needed for triggering motor response in case of GBM tumor compared to a slowly growing tumor (low-grade). Patients with low-grade gliomas (LGG) had statistically significantly higher KI values pre- and postoperatively than patients with GBM (p<0.01). Using electrical stimulation of the cortex, a higher grade of resection of LGG could be achieved as compared with the group presenting with GBM (c2=5.281; df=1; p<0.05). Our findings and review of the results reported by other authors underline the necessity of routine application of electrical stimulation of the cerebral cortex in order to identify the primary motor field (M1).

Ključne riječi
Motor cortex; Electrical stimulation therapy; Brain neoplasms; Glioblastoma – surgery; Glioma – surgery

Hrčak ID: 154823

URI
https://hrcak.srce.hr/154823

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Posjeta: 514 *