Acta clinica Croatica, Vol. 54. No. 4., 2015.
Izvorni znanstveni članak
Clinical and echocardiographic findings in newborns of diabetic mothers
Monica G. Hăşmăşanu
; Department of Neonatology, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; Department of Neonatology, Cluj-Napoca Emergency Clinical County Hospital, Cluj-Napoca, Romania
Sorana D. Bolboacă
orcid.org/0000-0002-2342-4311
; Department of Medical Informatics and Biostatistics,Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Melinda Matya
; Department of Neonatology, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; Department of Neonatology, Cluj-Napoca Emergency Clinical County Hospital, Cluj-Napoca, Romania
Gabriela C. Zaharie
; Department of Neonatology, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; Department of Neonatology, Cluj-Napoca Emergency Clinical County Hospital, Cluj-Napoca, Romania
Sažetak
The aim of the study was to assess the use of echocardiographic measurements in newborns of diabetic mothers. Maternal diabetes is associated with an increased risk of morbidity and mortality in pregnancy and in perinatal period. Thirty-five newborns of diabetic mothers (pregestational or gestational diabetes; case group) and thirty-five controls (control group), born between January 2009 and December 2012 in Cluj-Napoca (north-west of Romania), were included in this study. A Logiq e ultrasound with an 8 MHz transducer was used to measure echocardiographic parameters. The interventricular septal thickness in case group was higher as compared with control group (at end systole = 6.61±1.64 mm vs. 5.75±0.95 mm, p=0.0371; at end diastole = 4.61±1.59 mm vs. 3.42±0.70 mm, p=0.0001). A risk ratio of 2.333 (0.656, 8.298) was obtained for septal hypertrophy. A higher proportion of septal hypertrophy was identified in the newborns of mothers with
gestational diabetes compared to the newborns of pregestational diabetes mothers (p=0.0058). The mean birth weight was significantly higher in newborns of diabetic mothers (3695.57±738.63) as compared with controls (3276.14±496.51; p=0.0071). Infants born to mothers with diabetes proved to be at a high risk of septal hypertrophy.
Ključne riječi
Infant, newborn; Pregnancy - complications; Diabetes mellitus; Echocardiography; Hypertrophy; Heart septum – pathology
Hrčak ID:
155285
URI
Datum izdavanja:
1.12.2015.
Posjeta: 1.596 *