Stručni rad
RISK FACTOR EVALUATION USED AS INDICATORS IN EARLY DETECTION OF RECURRENT VULVAR CANCER
Miodrag Milojković
Mirjana Rubin
Milanka Mrčela
Sažetak
Objective. To evaluate risk factors, already present during the primary treatment of squamous cell carcinoma¬ of the vulva, which can be used as indicators in detection of recurrent vulvar cancer cases. Material and Methods. The retrospective data analysis consists of 32 patients with squamous cell carcinoma of the vulva, who were treated at the Department of Gynaecology and Obstetrics of Clinical hospital Osijek in the period from January 1 1993 till December 31 2000. Results. Of the risk factors, only two have been useful in detection of recurrent vulvar cancer cases: the tumor thickness 3.4 mm and the depth of stroma invasion 3.0 mm. Both risk factors have been noticed in the primary treatment of squamous cell carcinoma of the vulva and in 87.5% of the patients who during follow-up period developed recurrent vulvar cancer; both factors were present in 55.0% patients who did not develop recurrent vulvar cancer during follow-up period. Therefore, we can say that the sensitivity of both factors, used in early detection of recurrent vulvar cancer is 87.5%, specificity 45.0% and predictive value 48.8%. Conclusion. The estimation of tumor thickness and the level of stroma invasion during primary treatment of squamous cell carcinoma of the vulva can be used to select patients who would require a closer follow-up for a longer period in order to detect and treat recurrent vulvar cancer on time.
Ključne riječi
squamous cell carcinoma of the vulva; recurrent vulvar cancer; risk factors; prediction
Hrčak ID:
15591
URI
Datum izdavanja:
1.9.2004.
Posjeta: 1.694 *