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Original scientific paper

PINEAL GLAND VOLUME IN SCHIZOPHRENIA AND MOOD DISORDERS

Ebru Fındıklı ; Department of Psychiatry, Medical Faculty, Kahramanmaraş Sutcu Imam University, Kahramanmaras, Turkey
Mehmet Fatih Inci ; Department of Radiology, Medical Faculty, Katip Çelebi University, Izmir, Turkey
Mustafa Gökçe ; Department of Neurology, Medical Faculty, Kahramanmaraş Sutcu Imam University, Kahramanmaras, Turkey
Hüseyin Avni Fındıklı ; Department of Internal Medicine, Medical Faculty, Adıyaman University, Adıyaman, Turkey
Hatice Altun ; Department of Child and Adolescent Psychiatry, Kahramanmaraş Sutcu Imam University, Medical Faculty, Kahramanmaras, Turkey
Mehmet Fatih Karaaslan ; Department of Psychiatry, Medical Faculty, Kahramanmaraş Sutcu Imam University, Kahramanmaras, Turkey

Fulltext: english, pdf (238 KB) pages 0-158 downloads: 885* cite
APA 6th Edition
Fındıklı, E., Fatih Inci, M., Gökçe, M., Avni Fındıklı, H., Altun, H. & Fatih Karaaslan, M. (2015). PINEAL GLAND VOLUME IN SCHIZOPHRENIA AND MOOD DISORDERS. Psychiatria Danubina, 27 (2), 0-158. Retrieved from https://hrcak.srce.hr/162389
MLA 8th Edition
Fındıklı, Ebru, et al. "PINEAL GLAND VOLUME IN SCHIZOPHRENIA AND MOOD DISORDERS." Psychiatria Danubina, vol. 27, no. 2, 2015, pp. 0-158. https://hrcak.srce.hr/162389. Accessed 31 May 2020.
Chicago 17th Edition
Fındıklı, Ebru, Mehmet Fatih Inci, Mustafa Gökçe, Hüseyin Avni Fındıklı, Hatice Altun and Mehmet Fatih Karaaslan. "PINEAL GLAND VOLUME IN SCHIZOPHRENIA AND MOOD DISORDERS." Psychiatria Danubina 27, no. 2 (2015): 0-158. https://hrcak.srce.hr/162389
Harvard
Fındıklı, E., et al. (2015). 'PINEAL GLAND VOLUME IN SCHIZOPHRENIA AND MOOD DISORDERS', Psychiatria Danubina, 27(2), pp. 0-158. Available at: https://hrcak.srce.hr/162389 (Accessed 31 May 2020)
Vancouver
Fındıklı E, Fatih Inci M, Gökçe M, Avni Fındıklı H, Altun H, Fatih Karaaslan M. PINEAL GLAND VOLUME IN SCHIZOPHRENIA AND MOOD DISORDERS. Psychiatria Danubina [Internet]. 2015 [cited 2020 May 31];27(2):0-158. Available from: https://hrcak.srce.hr/162389
IEEE
E. Fındıklı, M. Fatih Inci, M. Gökçe, H. Avni Fındıklı, H. Altun and M. Fatih Karaaslan, "PINEAL GLAND VOLUME IN SCHIZOPHRENIA AND MOOD DISORDERS", Psychiatria Danubina, vol.27, no. 2, pp. 0-158, 2015. [Online]. Available: https://hrcak.srce.hr/162389. [Accessed: 31 May 2020]

Abstracts
Background: The majority of patients with schizophrenia and mood disorders have disruptions in sleep and circadian rhythm.
Melatonin, which is secreted by the human pineal gland, plays an important role in sleep and circadian rhythm. The aim of the
present study was to evaluate and compare pineal gland volumes in patients with schizophrenia and mood disorders.
Subjects and methods: We retrospectively evaluated the pineal gland volumes of 80 cases, including 16 cases of unipolar
depression, 17 cases of bipolar disorder, 17 cases of schizophrenia, and 30 controls. The total pineal gland volume of all cases was
measured via magnetic resonance images, and the total mean pineal volume of each group was compared.
Results: The mean pineal volumes of patients with schizophrenia, bipolar disorder, unipolar depression, and the controls were
83.55±10.11 mm³, 93.62±11.00 mm³, 95.19±11.61 mm³ and 99.73±12.03 mm³, respectively. The mean pineal gland volume of the
patients with schizophrenia was significantly smaller than those of the other groups.
Conclusions: Our data show that patients with schizophrenia have smaller pineal gland volumes, and this deviation in pineal
gland morphology is not seen in those with mood disorders. We hypothesize that volumetric changes in the pineal gland of patients
with schizophrenia may be involved in the pathophysiology of this illness.

Keywords
pineal gland volume – MRI - bipolar disorder - unipolar depression - schizophrenia

Hrčak ID: 162389

URI
https://hrcak.srce.hr/162389

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