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INCREASED NEUTROPHIL/LYMPHOCTYE RATIO IN PATIENTS WITH BIPOLAR DISORDER: A PRELIMINARY STUDY

Uğur Çakır
Taha Can Tuman
Osman Yıldırım

Puni tekst: engleski, pdf (248 KB) str. 0-184 preuzimanja: 239* citiraj
APA 6th Edition
Çakır, U., Can Tuman, T. i Yıldırım, O. (2015). INCREASED NEUTROPHIL/LYMPHOCTYE RATIO IN PATIENTS WITH BIPOLAR DISORDER: A PRELIMINARY STUDY. Psychiatria Danubina, 27 (2), 0-184. Preuzeto s https://hrcak.srce.hr/162394
MLA 8th Edition
Çakır, Uğur, et al. "INCREASED NEUTROPHIL/LYMPHOCTYE RATIO IN PATIENTS WITH BIPOLAR DISORDER: A PRELIMINARY STUDY." Psychiatria Danubina, vol. 27, br. 2, 2015, str. 0-184. https://hrcak.srce.hr/162394. Citirano 30.03.2020.
Chicago 17th Edition
Çakır, Uğur, Taha Can Tuman i Osman Yıldırım. "INCREASED NEUTROPHIL/LYMPHOCTYE RATIO IN PATIENTS WITH BIPOLAR DISORDER: A PRELIMINARY STUDY." Psychiatria Danubina 27, br. 2 (2015): 0-184. https://hrcak.srce.hr/162394
Harvard
Çakır, U., Can Tuman, T., i Yıldırım, O. (2015). 'INCREASED NEUTROPHIL/LYMPHOCTYE RATIO IN PATIENTS WITH BIPOLAR DISORDER: A PRELIMINARY STUDY', Psychiatria Danubina, 27(2), str. 0-184. Preuzeto s: https://hrcak.srce.hr/162394 (Datum pristupa: 30.03.2020.)
Vancouver
Çakır U, Can Tuman T, Yıldırım O. INCREASED NEUTROPHIL/LYMPHOCTYE RATIO IN PATIENTS WITH BIPOLAR DISORDER: A PRELIMINARY STUDY. Psychiatria Danubina [Internet]. 2015 [pristupljeno 30.03.2020.];27(2):0-184. Dostupno na: https://hrcak.srce.hr/162394
IEEE
U. Çakır, T. Can Tuman i O. Yıldırım, "INCREASED NEUTROPHIL/LYMPHOCTYE RATIO IN PATIENTS WITH BIPOLAR DISORDER: A PRELIMINARY STUDY", Psychiatria Danubina, vol.27, br. 2, str. 0-184, 2015. [Online]. Dostupno na: https://hrcak.srce.hr/162394. [Citirano: 30.03.2020.]

Sažetak
Background: In this study, it has been aimed to investigate whether neutrophil–lymphocyte ratio (NLR) was higher in non-obese
patients with bipolar disorder (BD) than in a healthy control group matched for age, sex, and body mass index, and also to
determine if there was an interaction between NLR and severity of the bipolar disorder.
Subjects and methods: In this retrospective study, 103 non-obese patients with BD and 126 healthy control subjects were
analyzed for complete blood count. The Young Mania Rating Scale (YMRS) was used to determine the severity of the disorder.
Results: The NLR was higher in female patients than in female comparison subjects (3.2±2.2; versus 1.7±0.4) (p<0.001). Also,
compared with the healthy male subjects, the male patients had significantly higher neutrophil/lymphocyte ratio (3.3±2.4; versus
2.0±0.7) (p<0.001). In the patients with bipolar disorder, NLR did not significantly correlate with severity (as measured with the
YMRS) (r=0.052; p=0.204) and duration of the disorder (r=0.045; p=0.301).
Conclusions: Results of this study revealed that patients with bipolar disorder have statistically significant elevated NRL than
healthy compares. According to this finding, elevated levels of NLR may be involved in inflammatory pathophysiology of bipolar
disorder. Further studies are needed for a better understanding of the mechanism between elevation of NRL in patients with bipolar
disorder.

Ključne riječi
lymphocyte – neutrophil - neutrophil/lymphocyte ratio – bipolar disorder – inflammation

Hrčak ID: 162394

URI
https://hrcak.srce.hr/162394

Posjeta: 320 *