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FILLAGRIN – MULTIFUNCTIONAL PROTEIN

IVANA ČEPELAK ; University of Zagreb, Faculty of Pharmaceutics and Biochemistry, Zagreb, Croatia
SLAVICA DODIG ; University of Zagreb, Faculty of Pharmaceutics and Biochemistry, Zagreb, Croatia
JELENA FILIPOVIĆ GRČIĆ ; University of Zagreb, Faculty of Pharmaceutics and Biochemistry, Zagreb, Croatia

Puni tekst: hrvatski, pdf (310 KB) str. 125-130 preuzimanja: 784* citiraj
APA 6th Edition
ČEPELAK, I., DODIG, S. i FILIPOVIĆ GRČIĆ, J. (2016). FILAGRIN - MULTIFUNKCIJSKI PROTEIN. Acta medica Croatica, 70 (2), 125-130. Preuzeto s https://hrcak.srce.hr/165171
MLA 8th Edition
ČEPELAK, IVANA, et al. "FILAGRIN - MULTIFUNKCIJSKI PROTEIN." Acta medica Croatica, vol. 70, br. 2, 2016, str. 125-130. https://hrcak.srce.hr/165171. Citirano 23.09.2021.
Chicago 17th Edition
ČEPELAK, IVANA, SLAVICA DODIG i JELENA FILIPOVIĆ GRČIĆ. "FILAGRIN - MULTIFUNKCIJSKI PROTEIN." Acta medica Croatica 70, br. 2 (2016): 125-130. https://hrcak.srce.hr/165171
Harvard
ČEPELAK, I., DODIG, S., i FILIPOVIĆ GRČIĆ, J. (2016). 'FILAGRIN - MULTIFUNKCIJSKI PROTEIN', Acta medica Croatica, 70(2), str. 125-130. Preuzeto s: https://hrcak.srce.hr/165171 (Datum pristupa: 23.09.2021.)
Vancouver
ČEPELAK I, DODIG S, FILIPOVIĆ GRČIĆ J. FILAGRIN - MULTIFUNKCIJSKI PROTEIN. Acta medica Croatica [Internet]. 2016 [pristupljeno 23.09.2021.];70(2):125-130. Dostupno na: https://hrcak.srce.hr/165171
IEEE
I. ČEPELAK, S. DODIG i J. FILIPOVIĆ GRČIĆ, "FILAGRIN - MULTIFUNKCIJSKI PROTEIN", Acta medica Croatica, vol.70, br. 2, str. 125-130, 2016. [Online]. Dostupno na: https://hrcak.srce.hr/165171. [Citirano: 23.09.2021.]

Sažetak
Effective physical, chemical, biochemical and immune function of the skin requires a corresponding structure of the epidermis. Filaggrin, one of epidermal proteins, is essential for the formation of corneocytes and intracellular metabolites, which in turn contribute to maintaining the stratum corneum humidity and acidic pH of the skin surface. However, a number of profi laggrin gene mutations have been described, as well as different infl ammatory conditions and different external factors that all resulted in fi laggrin defi ciency. Filaggrin defi ciency is recorded in different skin diseases and discoveries related to metabolic processing of fi laggrin point to new goals in therapeutic strategies. In this preview, the main properties
of the formation and metabolism of fi laggrin are described, as well as clinical implications of fi laggrin defi ciency in the etiopathogenesis of some skin diseases.

Ključne riječi
stratum corneum; fillaggrin, profillaggrin; natural moisturizing factor; atopic dermatitis

Hrčak ID: 165171

URI
https://hrcak.srce.hr/165171

[hrvatski]

Posjeta: 1.135 *