hrcak mascot   Srce   HID

Izvorni znanstveni članak

Cardiovascular Comorbidities in Patients with Psoriasis: Risk Profile Including Carotide Ultrasonography Assessed in Hospital-based Case Control Study

Jana Votrubova ; Department of Dermatovenereology, 2nd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
Katerina Juzlova ; Department of Dermatovenereology, 2nd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
Martina Dzambova ; Department of Dermatovenereology, 2nd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
Jana Hercogova ; Department of Dermatovenereology, 2nd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
Dana Gopfertova ; Department of Epidemiology, 2nd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
Zdenek Smerhovsky ; Department of Epidemiology, 2nd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic

Puni tekst: engleski, PDF (157 KB) str. 187-187 preuzimanja: 198* citiraj
APA 6th Edition
Votrubova, J., Juzlova, K., Dzambova, M., Hercogova, J., Gopfertova, D. i Smerhovsky, Z. (2016). Cardiovascular Comorbidities in Patients with Psoriasis: Risk Profile Including Carotide Ultrasonography Assessed in Hospital-based Case Control Study. Acta Dermatovenerologica Croatica, 24 (3), 187-187. Preuzeto s https://hrcak.srce.hr/165614
MLA 8th Edition
Votrubova, Jana, et al. "Cardiovascular Comorbidities in Patients with Psoriasis: Risk Profile Including Carotide Ultrasonography Assessed in Hospital-based Case Control Study." Acta Dermatovenerologica Croatica, vol. 24, br. 3, 2016, str. 187-187. https://hrcak.srce.hr/165614. Citirano 28.10.2021.
Chicago 17th Edition
Votrubova, Jana, Katerina Juzlova, Martina Dzambova, Jana Hercogova, Dana Gopfertova i Zdenek Smerhovsky. "Cardiovascular Comorbidities in Patients with Psoriasis: Risk Profile Including Carotide Ultrasonography Assessed in Hospital-based Case Control Study." Acta Dermatovenerologica Croatica 24, br. 3 (2016): 187-187. https://hrcak.srce.hr/165614
Harvard
Votrubova, J., et al. (2016). 'Cardiovascular Comorbidities in Patients with Psoriasis: Risk Profile Including Carotide Ultrasonography Assessed in Hospital-based Case Control Study', Acta Dermatovenerologica Croatica, 24(3), str. 187-187. Preuzeto s: https://hrcak.srce.hr/165614 (Datum pristupa: 28.10.2021.)
Vancouver
Votrubova J, Juzlova K, Dzambova M, Hercogova J, Gopfertova D, Smerhovsky Z. Cardiovascular Comorbidities in Patients with Psoriasis: Risk Profile Including Carotide Ultrasonography Assessed in Hospital-based Case Control Study. Acta Dermatovenerol Croat. [Internet]. 2016 [pristupljeno 28.10.2021.];24(3):187-187. Dostupno na: https://hrcak.srce.hr/165614
IEEE
J. Votrubova, K. Juzlova, M. Dzambova, J. Hercogova, D. Gopfertova i Z. Smerhovsky, "Cardiovascular Comorbidities in Patients with Psoriasis: Risk Profile Including Carotide Ultrasonography Assessed in Hospital-based Case Control Study", Acta Dermatovenerologica Croatica, vol.24, br. 3, str. 187-187, 2016. [Online]. Dostupno na: https://hrcak.srce.hr/165614. [Citirano: 28.10.2021.]

Sažetak

Psoriasis is a chronic inflammatory disease and its comorbidities have attracted serious interest in recent years. The evidence that psoriasis is associated with systemic inflammation and significantly higher incidence of cardiovascular risk factors was already described. The results of published studies are highly variable, the conclusions are ambiguous and further epidemiological studies are needed for validation of published data. Therefore, we initiated a project aimed at identifying the carriership of cardiovascular risk factors including early stages of atherosclerosis that represent important comorbidities in patients with psoriasis.

We carried out a hospital-based case-control study. 189 patients with chronic plaque psoriasis were enrolled as cases. The group consisted of 378 patients with other skin diseases complying with the same restriction criteria were recruited to the study as the controls. All participants underwent physical examination, blood tests, measuring of blood pressure, waist circumference. Furthermore, in the subset of 117 cases and controls (matched 1:2) with no history of cardiovascular disease we evaluated the intima-media thickness (cIMT).

The results show higher prevalence of hypertension, hyperlipidaemia, waist circumference, weight, BMI and CRP level in patients with psoriasis than in controls. These parameters have been clearly demonstrated as risk factors for the development of cardiovascular diseases. The associations among psoriasis and diastolic blood pressure, BMI value and LDL cholesterol are statistically significant in the binary data logistic model as well. cIMT in patients  compared to controls was not significant.

Ključne riječi
Psoriasis is a chronic inflammatory disease and its comorbidities have attracted serious interest in recent years. The evidence that psoriasis is associated with systemic inflammation and significantly higher incidence of cardiovascular risk factors was a

Hrčak ID: 165614

URI
https://hrcak.srce.hr/165614

Posjeta: 375 *