A Tyrosine-Dependent Riboswitch Controls the Expression of a Tyrosyl-tRNA Synthetase from Acidithiobacillus ferrooxidans
Paula Bustamante
; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, 8380453, Chile
Oriana Salazar
; Centre for Biochemical Engineering and Biotechnology, Department of Chemical Engineering and Biotechnology, Faculty of Physical Sciences and Mathematics, University of Chile, Santiago, Chile
Héctor Garcías-Papayani
; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, 8380453, Chile
Pamela Alamos
; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, 8380453, Chile
Omar Orellana
; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, 8380453, Chile
APA 6th Edition Bustamante, P., Salazar, O., Garcías-Papayani, H., Alamos, P. i Orellana, O. (2016). A Tyrosine-Dependent Riboswitch Controls the Expression of a Tyrosyl-tRNA Synthetase from Acidithiobacillus ferrooxidans. Croatica Chemica Acta, 89 (2), 189-195. https://doi.org/10.5562/cca2832
MLA 8th Edition Bustamante, Paula, et al. "A Tyrosine-Dependent Riboswitch Controls the Expression of a Tyrosyl-tRNA Synthetase from Acidithiobacillus ferrooxidans." Croatica Chemica Acta, vol. 89, br. 2, 2016, str. 189-195. https://doi.org/10.5562/cca2832. Citirano 08.03.2021.
Chicago 17th Edition Bustamante, Paula, Oriana Salazar, Héctor Garcías-Papayani, Pamela Alamos i Omar Orellana. "A Tyrosine-Dependent Riboswitch Controls the Expression of a Tyrosyl-tRNA Synthetase from Acidithiobacillus ferrooxidans." Croatica Chemica Acta 89, br. 2 (2016): 189-195. https://doi.org/10.5562/cca2832
Harvard Bustamante, P., et al. (2016). 'A Tyrosine-Dependent Riboswitch Controls the Expression of a Tyrosyl-tRNA Synthetase from Acidithiobacillus ferrooxidans', Croatica Chemica Acta, 89(2), str. 189-195. https://doi.org/10.5562/cca2832
Vancouver Bustamante P, Salazar O, Garcías-Papayani H, Alamos P, Orellana O. A Tyrosine-Dependent Riboswitch Controls the Expression of a Tyrosyl-tRNA Synthetase from Acidithiobacillus ferrooxidans. Croatica Chemica Acta [Internet]. 2016 [pristupljeno 08.03.2021.];89(2):189-195. https://doi.org/10.5562/cca2832
IEEE P. Bustamante, O. Salazar, H. Garcías-Papayani, P. Alamos i O. Orellana, "A Tyrosine-Dependent Riboswitch Controls the Expression of a Tyrosyl-tRNA Synthetase from Acidithiobacillus ferrooxidans", Croatica Chemica Acta, vol.89, br. 2, str. 189-195, 2016. [Online]. https://doi.org/10.5562/cca2832
Sažetak Expression of aminoacyl-tRNA synthetases is regulated by a variety of mechanisms at the level of transcription or translation. A T-box dependent transcription termination / antitermination riboswitch system that responds to charged / uncharged tRNA regulates expression of aminoacyl tRNA synthetase genes in Gram-positive bacteria. TyrZ, the gene encoding tyrosyl-tRNA synthetase from Acidithiobacillus ferrooxidans, a Gram-negative acidophilic bacterium that participates in bioleaching of minerals, resembles the gene from Bacillus subtilis including the 5´-untranslated region encoding the riboswitch. Transcription of A. ferrooxidans tyrZ is induced by the presence of tyrosine by a mechanism involving antitermination of transcription. This mechanism is probably adapted to the low supply of amino acids of acidic environments of autotrophic bioleaching microorganisms.