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Arhiv za higijenu rada i toksikologiju, Vol. 23 No. 1, 1972.

Kratko priopćenje

Effect of ecological factors on the appearance of toxic porphyria. I. alcoholism and D-DALA

D. Dimov ; Institut za medicinska istraživanja i medicinu rada, JAZU, Zagreb
Danica Prpić-Majić ; Institut za medicinska istraživanja i medicinu rada, JAZU, Zagreb
T. Beritić ; Institut za medicinska istraživanja i medicinu rada, JAZU, Zagreb
Antonija Keršanc ; Institut za medicinska istraživanja i medicinu rada, JAZU, Zagreb
Višnja Karačić ; Institut za medicinska istraživanja i medicinu rada, JAZU, Zagreb

Puni tekst: hrvatski, pdf (6 MB) str. 11-17 preuzimanja: 43* citiraj
APA 6th Edition
Dimov, D., Prpić-Majić, D., Beritić, T., Keršanc, A. i Karačić, V. (1972). Utjecaj ekoloških faktora na pojavu toksičnih porfirija. I. alkoholizam i aktivnost dehidrataze delta-aminolevulinske kiseline. Arhiv za higijenu rada i toksikologiju, 23 (1), 11-17. Preuzeto s https://hrcak.srce.hr/168969
MLA 8th Edition
Dimov, D., et al. "Utjecaj ekoloških faktora na pojavu toksičnih porfirija. I. alkoholizam i aktivnost dehidrataze delta-aminolevulinske kiseline." Arhiv za higijenu rada i toksikologiju, vol. 23, br. 1, 1972, str. 11-17. https://hrcak.srce.hr/168969. Citirano 20.02.2019.
Chicago 17th Edition
Dimov, D., Danica Prpić-Majić, T. Beritić, Antonija Keršanc i Višnja Karačić. "Utjecaj ekoloških faktora na pojavu toksičnih porfirija. I. alkoholizam i aktivnost dehidrataze delta-aminolevulinske kiseline." Arhiv za higijenu rada i toksikologiju 23, br. 1 (1972): 11-17. https://hrcak.srce.hr/168969
Harvard
Dimov, D., et al. (1972). 'Utjecaj ekoloških faktora na pojavu toksičnih porfirija. I. alkoholizam i aktivnost dehidrataze delta-aminolevulinske kiseline', Arhiv za higijenu rada i toksikologiju, 23(1), str. 11-17. Preuzeto s: https://hrcak.srce.hr/168969 (Datum pristupa: 20.02.2019.)
Vancouver
Dimov D, Prpić-Majić D, Beritić T, Keršanc A, Karačić V. Utjecaj ekoloških faktora na pojavu toksičnih porfirija. I. alkoholizam i aktivnost dehidrataze delta-aminolevulinske kiseline. Arh Hig Rada Toksikol. [Internet]. 1972 [pristupljeno 20.02.2019.];23(1):11-17. Dostupno na: https://hrcak.srce.hr/168969
IEEE
D. Dimov, D. Prpić-Majić, T. Beritić, A. Keršanc i V. Karačić, "Utjecaj ekoloških faktora na pojavu toksičnih porfirija. I. alkoholizam i aktivnost dehidrataze delta-aminolevulinske kiseline", Arhiv za higijenu rada i toksikologiju, vol.23, br. 1, str. 11-17, 1972. [Online]. Dostupno na: https://hrcak.srce.hr/168969. [Citirano: 20.02.2019.]

Sažetak
The activity of delta-aminolevulinic acid dehydratase (D-DALA) in chronic alcoholics (N = 51) was analysed along with the parallel determination of the concentration of delta-amninolevulinic acid (DALA) in a single urine sample. In 12 patients with the chronic liver lesions the elimination of hem precursors in the urine and the activity of D-DALA in the blood were also analysed. The results have shown that in chronic alcoholics over 500/o of subjects had a reduced D-DALA activity, while the DALA elimination was slightly increased in 14% of subjects. In patients with chronic liver lesions the elimination of porphyrins and their precursors was normal while the activity of D-DALA was slightly inhibited in 6 patients. Although the results obtained in the group of chronic alcoholics speak for the effect of ethyl alcohol on the D-DALA activity, no conclusive statement is possible because some other known potential inhibitors of this enzyme cannot be ruled out. Also, in order to give a definite judgment about the inhibition of D-DALA in chronic liver diseases, it would be necessary to examine a larger number of patients with alcohol-induced liver lesions.

Hrčak ID: 168969

URI
https://hrcak.srce.hr/168969

[hrvatski]

Posjeta: 102 *