Stručni rad
Carbamazepine overdose presenting as a diabetes insipidus – like condition in a child
Madhuradhar Chegondi
; Division of Critical Care Medicine Nemours Children’s Hospital 13535 Nemours Parkway, Orlando, FL 32827
Sažetak
Carbamazepine is a commonly used antiepileptic medication. In overdoses it can produce various side effects involving neurological, cardiac, hematological and endocrinal systems. Inappropriate secretion of Anti Diuretic Hormone (ADH) is a well-known complication of carbamazepine toxicity. We are reporting an unusual complication in an adolescent girl with intentional carbamazepine overdose. A sixteen year old female with carbamazepine ingestion presented to our hospital with altered sensorium. On admission she was found to have a very high serum carbamazepine level and metabolic acidosis. In contrast to the possible inappropriate secretion of ADH, as an adverse effect of carbamazepine, her hospital course was complicated with a diabetes insipidus – like condition following treatment with multiple doses of activated charcoal and sodium bicarbonate therapy.
Ključne riječi
Carbamazepine; Diabetes Insipidus; activated charcoal; child
Hrčak ID:
170143
URI
Datum izdavanja:
1.12.2015.
Posjeta: 778 *