Izvorni znanstveni članak
Influence of lactation on 85Sr and 45Ca mobilization from the skeleton
B. Momčilović
; Institut za medicinska istraživanja i medicinu rada Jugoslavenske akademije znanosti i umjetnosti, Zagreb
A. Duraković
; Institut za medicinska istraživanja i medicinu rada Jugoslavenske akademije znanosti i umjetnosti, Zagreb
Krista Kostial
; Institut za medicinska istraživanja i medicinu rada Jugoslavenske akademije znanosti i umjetnosti, Zagreb
Sažetak
The purpose of our work was to find out from which part of mother's bone calcium and strontium are mobilized during the lactation period. We also wanted to estimate the time of maximal transfer of these minerals from mother to newborns. The experiments were performed on three groups of four month-old albino rats which received radioactive isotopes of calcium (45Ca) and strontium (85Sr) by a single intraperitoneal injection at various time intervals so as to enable the labeling of different parts of the mother's skeleton. The first group received radioactive isotopes before the gestation period, the second at the onset of lactation, while the third group received them during the lactation period. The fraction of radioactive isotopes retained in the skeleton was estimated on 3rd, 12th and 20th day of lactation in the first and second group of rats and 48 hours after the radioactive application in the third group of animals. Our results indicate that the minerals transferred to the litter are mobilized mainly from the superficial -or exchangeable parts of the mother's skeleton. A small fraction of minerals originates from deeper layers of the bone. The transfer of minerals from mother to newborns is highest during the second part of the lactation period. The fraction of calcium mobilized to the litter is about twice as high as that of strontium.
Ključne riječi
Hrčak ID:
170957
URI
Datum izdavanja:
9.12.1971.
Posjeta: 758 *