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DRUG INDUCED ALLERGIC INTERSTITIAL NEPHRITIS

Krešimir Galešić
Ingrid Prkačin
Miroslav Tišljar
Ivica Horvatić
Danica Galešić Ljubanović

Puni tekst: hrvatski, pdf (379 KB) str. 0-0 preuzimanja: 224* citiraj
APA 6th Edition
Galešić, K., Prkačin, I., Tišljar, M., Horvatić, I. i Galešić Ljubanović, D. (2011). ALERGIJSKI INTERSTICIJSKI NEFRITIS UZROKOVAN LIJEKOVIMA. Liječnički vjesnik, 133 (7-8), 0-0. Preuzeto s https://hrcak.srce.hr/171842
MLA 8th Edition
Galešić, Krešimir, et al. "ALERGIJSKI INTERSTICIJSKI NEFRITIS UZROKOVAN LIJEKOVIMA." Liječnički vjesnik, vol. 133, br. 7-8, 2011, str. 0-0. https://hrcak.srce.hr/171842. Citirano 15.10.2019.
Chicago 17th Edition
Galešić, Krešimir, Ingrid Prkačin, Miroslav Tišljar, Ivica Horvatić i Danica Galešić Ljubanović. "ALERGIJSKI INTERSTICIJSKI NEFRITIS UZROKOVAN LIJEKOVIMA." Liječnički vjesnik 133, br. 7-8 (2011): 0-0. https://hrcak.srce.hr/171842
Harvard
Galešić, K., et al. (2011). 'ALERGIJSKI INTERSTICIJSKI NEFRITIS UZROKOVAN LIJEKOVIMA', Liječnički vjesnik, 133(7-8), str. 0-0. Preuzeto s: https://hrcak.srce.hr/171842 (Datum pristupa: 15.10.2019.)
Vancouver
Galešić K, Prkačin I, Tišljar M, Horvatić I, Galešić Ljubanović D. ALERGIJSKI INTERSTICIJSKI NEFRITIS UZROKOVAN LIJEKOVIMA. Liječnički vjesnik [Internet]. 2011 [pristupljeno 15.10.2019.];133(7-8):0-0. Dostupno na: https://hrcak.srce.hr/171842
IEEE
K. Galešić, I. Prkačin, M. Tišljar, I. Horvatić i D. Galešić Ljubanović, "ALERGIJSKI INTERSTICIJSKI NEFRITIS UZROKOVAN LIJEKOVIMA", Liječnički vjesnik, vol.133, br. 7-8, str. 0-0, 2011. [Online]. Dostupno na: https://hrcak.srce.hr/171842. [Citirano: 15.10.2019.]

Sažetak
The allergic interstitial nephritis (AIN) is a rare renal disorder which is commonly clinically presented with an acute renal failure. AIN is the most frequent result of the hypersensitivity related to drugs (most often antibiotics). In the patients with clinical suspicion to a drug related AIN, kidney biopsy is the most important diagnostic procedure. Except of causative drug discontinuation, AIN therapy is based on high dose glucocorticoids 1 mg/kg/day with dose tapering during consecutive 3 months. In the present work, we have shown 10 patients with drug induced AIN. We identified 4 causative drug groups among which most frequent were antibiotics. In clinical presentation of our patients acute renal failure was dominant and median of baseline serum creatinine was 497.5 µmol/L. In all patients the kidney biopsy was performed and nine patients (90%) have been treated with recommended glucocorticoid regimen, additionally, in 3 patients hemodialysis was introduced. In all patients, reduction in serum creatinine value was achieved with serum creatinine median of 152 µmol/L after a three-month glucocorticoid treatment (p=0.018).

Ključne riječi
Nephritis, interstitial – chemically induced, pathology, drug therapy; Acute kidney injury – chemically induced; Glucocorticoids – therapeutic use; Drug hypersensitivity – complications

Hrčak ID: 171842

URI
https://hrcak.srce.hr/171842

[hrvatski]

Posjeta: 349 *