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THE ROLE OF OXIDATIVE STRESS AND IRON IN PATHOPHYSIOLOGY OF ROSACEA

Vesna Sredoja Tišma
Marija Poljak-Blaži

Puni tekst: hrvatski, pdf (179 KB) str. 0-0 preuzimanja: 51* citiraj
APA 6th Edition
Sredoja Tišma, V. i Poljak-Blaži, M. (2011). ULOGA OKSIDACIJSKOG STRESA I ŽELJEZA U PATOFIZIOLOGIJI ROZACEJE. Liječnički vjesnik, 133 (7-8), 0-0. Preuzeto s https://hrcak.srce.hr/171844
MLA 8th Edition
Sredoja Tišma, Vesna i Marija Poljak-Blaži. "ULOGA OKSIDACIJSKOG STRESA I ŽELJEZA U PATOFIZIOLOGIJI ROZACEJE." Liječnički vjesnik, vol. 133, br. 7-8, 2011, str. 0-0. https://hrcak.srce.hr/171844. Citirano 19.10.2019.
Chicago 17th Edition
Sredoja Tišma, Vesna i Marija Poljak-Blaži. "ULOGA OKSIDACIJSKOG STRESA I ŽELJEZA U PATOFIZIOLOGIJI ROZACEJE." Liječnički vjesnik 133, br. 7-8 (2011): 0-0. https://hrcak.srce.hr/171844
Harvard
Sredoja Tišma, V., i Poljak-Blaži, M. (2011). 'ULOGA OKSIDACIJSKOG STRESA I ŽELJEZA U PATOFIZIOLOGIJI ROZACEJE', Liječnički vjesnik, 133(7-8), str. 0-0. Preuzeto s: https://hrcak.srce.hr/171844 (Datum pristupa: 19.10.2019.)
Vancouver
Sredoja Tišma V, Poljak-Blaži M. ULOGA OKSIDACIJSKOG STRESA I ŽELJEZA U PATOFIZIOLOGIJI ROZACEJE. Liječnički vjesnik [Internet]. 2011 [pristupljeno 19.10.2019.];133(7-8):0-0. Dostupno na: https://hrcak.srce.hr/171844
IEEE
V. Sredoja Tišma i M. Poljak-Blaži, "ULOGA OKSIDACIJSKOG STRESA I ŽELJEZA U PATOFIZIOLOGIJI ROZACEJE", Liječnički vjesnik, vol.133, br. 7-8, str. 0-0, 2011. [Online]. Dostupno na: https://hrcak.srce.hr/171844. [Citirano: 19.10.2019.]

Sažetak
Rosacea is a common skin disease of unknown etiology. The aim of the present paper is to explain the role of oxidative stress triggered by UV light and iron metabolism in the pathophysiology of rosacea. It was recently described that the number of ferritin positive cells was significantly higher in skin samples of rosacea patients compared to controls of healthy skin samples. The presence of ferritin was significantly higher in patients with the severe stage of disease. In addition, serum peroxide levels were significantly higher and serum total antioxidative potential levels were significantly lower in rosacea patients than in healthy controls. These results support the role of oxidative stress and affected metabolism of iron in etiology of rosacea. The higher presence of ferritin in skin cells of rosacea patients explains the exacerbation of symptoms by exposure to UV light, that releases ferritin free iron, which is fundamental in the generation of oxidative stress.

Ključne riječi
Rosacea – physiopathology, blood, metabolism; Ferritins – metabolism; Peroxides – blood; Oxidative stress – physiology; Antioxidants – metabolism; Skin – pathology, metabolism, radiation effects; Ultraviolet rays

Hrčak ID: 171844

URI
https://hrcak.srce.hr/171844

[hrvatski]

Posjeta: 110 *