Liječnički vjesnik, Vol. 134 No. 1-2, 2012.
Pregledni rad
INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM OF THE PANCREAS: CASE REPORT AND REVIEW OF THE LITERATURE
Hrvoje Iveković
Nadan Rustemović
Milorad Opačić
Ognjan Deban
Boško Romić
Jasminka Jakić Razumović
Rajko Ostojić
Roland Pulanić
Boris Vucelić
Sažetak
Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is a relatively rare clinical entity with a main characteristic being mucus production. Extension of IPMN along pancretic ducts and mucus production lead to ductal obstruction and dilatation, resulting in recurrent episodes of acute pancreatitis. Molecular background of IPMN-a comprises several aberrations, with the K-ras gene mutation being the likely trigger that initiates further genetic changes. Due to its indolent nature, IPMN is most commonly diagnosed in the 7th decade of life. Depending on the histology type, IPMN has a malignant potential. Therefore, surgical therapy remains a »gold standard« of treatment. Insidious, slow progression of the disease and absence of symptoms in a certain number of patients makes diagnostic approach to this entity difficult. In this paper we present a patient with IPMN of the pancreas, in whom the episodes of acute pancreatitis had been present for 22 years.
Ključne riječi
Adenocarcinoma, mucinous – diagnosis, surgery; Carcinoma, papilllary – diagnosis, surgery; Pancreatic neoplasms – diagnosis, surgery; Pancreatic ducts – pathology
Hrčak ID:
172392
URI
Datum izdavanja:
29.2.2012.
Posjeta: 4.332 *