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Stručni rad


Dinka Pavičić Baldani
Lana Škrgatić
Velimir Šimunić
Vesna Elveđi Gašparović
Blaž Geršak

Puni tekst: hrvatski, pdf (302 KB) str. 0-0 preuzimanja: 165* citiraj
APA 6th Edition
Pavičić Baldani, D., Škrgatić, L., Šimunić, V., Elveđi Gašparović, V. i Geršak, B. (2015). HORMONSKO NADOMJESNO LIJEČENJE I VENSKE TROMBOEMBOLIJE. Liječnički vjesnik, 137 (1-2), 0-0. Preuzeto s
MLA 8th Edition
Pavičić Baldani, Dinka, et al. "HORMONSKO NADOMJESNO LIJEČENJE I VENSKE TROMBOEMBOLIJE." Liječnički vjesnik, vol. 137, br. 1-2, 2015, str. 0-0. Citirano 13.06.2021.
Chicago 17th Edition
Pavičić Baldani, Dinka, Lana Škrgatić, Velimir Šimunić, Vesna Elveđi Gašparović i Blaž Geršak. "HORMONSKO NADOMJESNO LIJEČENJE I VENSKE TROMBOEMBOLIJE." Liječnički vjesnik 137, br. 1-2 (2015): 0-0.
Pavičić Baldani, D., et al. (2015). 'HORMONSKO NADOMJESNO LIJEČENJE I VENSKE TROMBOEMBOLIJE', Liječnički vjesnik, 137(1-2), str. 0-0. Preuzeto s: (Datum pristupa: 13.06.2021.)
Pavičić Baldani D, Škrgatić L, Šimunić V, Elveđi Gašparović V, Geršak B. HORMONSKO NADOMJESNO LIJEČENJE I VENSKE TROMBOEMBOLIJE. Liječnički vjesnik [Internet]. 2015 [pristupljeno 13.06.2021.];137(1-2):0-0. Dostupno na:
D. Pavičić Baldani, L. Škrgatić, V. Šimunić, V. Elveđi Gašparović i B. Geršak, "HORMONSKO NADOMJESNO LIJEČENJE I VENSKE TROMBOEMBOLIJE", Liječnički vjesnik, vol.137, br. 1-2, str. 0-0, 2015. [Online]. Dostupno na: [Citirano: 13.06.2021.]

Venous thromboembolism (VTE) is the most important side effect of using hormone replacement therapy (HRT). Biological and epidemiological studies have shown that oral administration of estrogen is associated with an increased risk of VTE compared to transdermal route of administration. Addition of progestogen to estrogen further increases the risk of VTE. Different pharmacological classes of progestogens differently contribute to the risk of VTE. Observational studies observed that the application of micronized progesterone and didrogesteron are safer regarding the risk of VTE compared to other progestins. These results should be further confirmed in the randomized studies. A personal or family history of VTE, existence of hereditary thrombophilia or/and multiple risk factors for VTE represent a strong contraindication to oral HRT use. In such persons the application of transdermal estrogen can be considered after careful individual evaluation of the benefits and risks. Transdermal estrogen should be also the first choice in overweight/obese women requiring HRT.

Ključne riječi
Venous thromboembolism – chemically induced; Hormone replacement therapy – adverse effects, methods; Estrogens – therapeutic use, adverse effects, administration and dosage; Administration, oral; Administration, cutaneous; Progestins – therapeutic use, adverse effects; Progesterone – theraputic use; Postmenopause

Hrčak ID: 172679



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