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HYPOKALEMIC METABOLIC ALKALOSIS – A REPORT OF SIX CASES

Krešimir Galešić
Ivica Horvatić
Mario Ilić
Martin Ćuk
Matija Crnogorac
Danica Galešić Ljubanović

Puni tekst: hrvatski, pdf (858 KB) str. 0-0 preuzimanja: 464* citiraj
APA 6th Edition
Galešić, K., Horvatić, I., Ilić, M., Ćuk, M., Crnogorac, M. i Galešić Ljubanović, D. (2016). HIPOKALIEMIJSKA METABOLIČKA ALKALOZA: PRIKAZ 6 SLUČAJEVA. Liječnički vjesnik, 138 (9-10), 0-0. Preuzeto s https://hrcak.srce.hr/172888
MLA 8th Edition
Galešić, Krešimir, et al. "HIPOKALIEMIJSKA METABOLIČKA ALKALOZA: PRIKAZ 6 SLUČAJEVA." Liječnički vjesnik, vol. 138, br. 9-10, 2016, str. 0-0. https://hrcak.srce.hr/172888. Citirano 16.10.2019.
Chicago 17th Edition
Galešić, Krešimir, Ivica Horvatić, Mario Ilić, Martin Ćuk, Matija Crnogorac i Danica Galešić Ljubanović. "HIPOKALIEMIJSKA METABOLIČKA ALKALOZA: PRIKAZ 6 SLUČAJEVA." Liječnički vjesnik 138, br. 9-10 (2016): 0-0. https://hrcak.srce.hr/172888
Harvard
Galešić, K., et al. (2016). 'HIPOKALIEMIJSKA METABOLIČKA ALKALOZA: PRIKAZ 6 SLUČAJEVA', Liječnički vjesnik, 138(9-10), str. 0-0. Preuzeto s: https://hrcak.srce.hr/172888 (Datum pristupa: 16.10.2019.)
Vancouver
Galešić K, Horvatić I, Ilić M, Ćuk M, Crnogorac M, Galešić Ljubanović D. HIPOKALIEMIJSKA METABOLIČKA ALKALOZA: PRIKAZ 6 SLUČAJEVA. Liječnički vjesnik [Internet]. 2016 [pristupljeno 16.10.2019.];138(9-10):0-0. Dostupno na: https://hrcak.srce.hr/172888
IEEE
K. Galešić, I. Horvatić, M. Ilić, M. Ćuk, M. Crnogorac i D. Galešić Ljubanović, "HIPOKALIEMIJSKA METABOLIČKA ALKALOZA: PRIKAZ 6 SLUČAJEVA", Liječnički vjesnik, vol.138, br. 9-10, str. 0-0, 2016. [Online]. Dostupno na: https://hrcak.srce.hr/172888. [Citirano: 16.10.2019.]

Sažetak
In this article six patients with hypokalemic metabolic alkalosis, classified as Bartter or Gitelman syndrome are presented. Both syndromes result from different gene mutation inducing impaired function of the transporters involved in sodium, chloride and potassium reapsorption in thick ascending limb of the loop of Henle and distal convoluted tubules. These syndromes typically present with hypokalemia, metabolic alkalosis, hyperreninemic hyperaldosteronism without hypertension, polyuria and muscle weakness. Other clinical characteristics may vary considerably, depending on the gene expression. Correct diagnosis is only possible using expensive and not-routinely available genetic testing. Routine laboratory tests, especially those considering serum and urine electrolytes, can help in recognizing these syndromes and therefore in timely beginning of treatment. The most important distinctive laboratory findings are serum magnesium concentration and urine calcium excretion. In Bartter syndrome typically there is hypercalciuria with or without hypomagnesemia, while in Gitelman syndrome typical findings are hypocalciuria and hypomagnesemia. Recognizing and treating these patients is important due to possible increased morbidity and mortality induced by severe electrolyte imbalance.

Ključne riječi
Bartter syndrome – diagnosis, genetics, therapy; Gitelman syndrome – diagnosis, genetics, therapy; Alkalosis – etiology, diagnosis, genetics; Hypokalemia – etiology, diagnosis, genetics; Renal tubular transport, inborn errors – genetics; Membrane transport proteins – genetics; Mutation; Kidney tubules, distal – pathology; Loop of henle – metabolism, pathology; Juxtaglomerular apparatus – pathology; Magnesium – blood; Calcium – urine; Hyperaldosteronism – etiologija

Hrčak ID: 172888

URI
https://hrcak.srce.hr/172888

[hrvatski]

Posjeta: 640 *