Croatica Chemica Acta, Vol. 62 No. 2A, 1989.
Izvorni znanstveni članak
The Molecular Structure of cis-4-Aza-A-homo-tetrahydro-a-santonin and trans-4- Aza- A- homo- tetrahydro-a-santonin Related to the Lactam Rule
Hiroaki Takayanagi
; School of Pharmaceutical Sciences, Kitasato University, Shirokane, Minato-ku Tokyo 108, Japan
Ikuyo Hara
; School of Pharmaceutical Sciences, Kitasato University, Shirokane, Minato-ku Tokyo 108, Japan
Motoaki Goto
; School of Pharmaceutical Sciences, Kitasato University, Shirokane, Minato-ku Tokyo 108, Japan
Haruo Ogura
; School of Pharmaceutical Sciences, Kitasato University, Shirokane, Minato-ku Tokyo 108, Japan
Sažetak
Stereochemistry of the titled compounds was determined by X-ray structure analysis. The seven-membered lactam rings of both compounds are in a quasi-chair conformation which agrees
with the lactam rule. The mean values of the C-NH-CO-C torsion angles are -6 ° and +5°, respectively, and these values
also agree with Klyne's hypothesis.
Ključne riječi
Hrčak ID:
175383
URI
Datum izdavanja:
30.6.1989.
Posjeta: 530 *