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Sinteza i karakterizacija N,N'-biskarbazolil azina i N,N'-karbazolilhidrazini i antimikrobni učinak

ISRAVEL ANTONY DANISH
KARNAM JAYARAMPILLAI
RAJENDRA PRASAD

Puni tekst: engleski, pdf (99 KB) str. 133-142 preuzimanja: 440* citiraj
APA 6th Edition
ANTONY DANISH, I., JAYARAMPILLAI, K. i PRASAD, R. (2004). Syntheses and characterisation of N,N'-biscarbazolyl azine and N,N'-carbazolyl hydrazine derivatives and their antimicrobial studies. Acta Pharmaceutica, 54 (2), 133-142. Preuzeto s https://hrcak.srce.hr/16821
MLA 8th Edition
ANTONY DANISH, ISRAVEL, et al. "Syntheses and characterisation of N,N'-biscarbazolyl azine and N,N'-carbazolyl hydrazine derivatives and their antimicrobial studies." Acta Pharmaceutica, vol. 54, br. 2, 2004, str. 133-142. https://hrcak.srce.hr/16821. Citirano 17.06.2019.
Chicago 17th Edition
ANTONY DANISH, ISRAVEL, KARNAM JAYARAMPILLAI i RAJENDRA PRASAD. "Syntheses and characterisation of N,N'-biscarbazolyl azine and N,N'-carbazolyl hydrazine derivatives and their antimicrobial studies." Acta Pharmaceutica 54, br. 2 (2004): 133-142. https://hrcak.srce.hr/16821
Harvard
ANTONY DANISH, I., JAYARAMPILLAI, K., i PRASAD, R. (2004). 'Syntheses and characterisation of N,N'-biscarbazolyl azine and N,N'-carbazolyl hydrazine derivatives and their antimicrobial studies', Acta Pharmaceutica, 54(2), str. 133-142. Preuzeto s: https://hrcak.srce.hr/16821 (Datum pristupa: 17.06.2019.)
Vancouver
ANTONY DANISH I, JAYARAMPILLAI K, PRASAD R. Syntheses and characterisation of N,N'-biscarbazolyl azine and N,N'-carbazolyl hydrazine derivatives and their antimicrobial studies. Acta Pharm. [Internet]. 2004 [pristupljeno 17.06.2019.];54(2):133-142. Dostupno na: https://hrcak.srce.hr/16821
IEEE
I. ANTONY DANISH, K. JAYARAMPILLAI i R. PRASAD, "Syntheses and characterisation of N,N'-biscarbazolyl azine and N,N'-carbazolyl hydrazine derivatives and their antimicrobial studies", Acta Pharmaceutica, vol.54, br. 2, str. 133-142, 2004. [Online]. Dostupno na: https://hrcak.srce.hr/16821. [Citirano: 17.06.2019.]

Sažetak
Reakcijom 1-okso-1,2,3,4-tetrahidrokarbazola 1a-e s hidrazin hidratom u apsolutnom etanolu dobiveni su derivati N,N'-biskarbazolilazina 2a-e, a s hidroksilamin hidrokloridom u etanolu, uz katalitičke količine piridina, 1-hidroksiimino-1,2,3,4-tetrahidrokarbazoli 3a-e. Redukcijom 3 s hidrazin hidratom u prisutnosti paladija na ugljenu nastali su derivati N,N'-karbazolil hidrazina 4a-e. Novosintetizirani spojevi su karakterizirani IR, 1H NMR i masenom spektroskopijom te elementarnom analizom. Spojevi 2, 3 i 4 su potencijalna antibakterijska i antimikotska sredstva. Najjače djelovanje pokazali su derivati 2e i 4e koji sadrže klor.

Ključne riječi
1-okso-1,2,3,4-tetrahidrokarbazoli; 1-hidroksiimino-1,2,3,4-tetrahidrokarbazoli; N,N'-biskarbazolilazini; N,N'-karbazolilhidrazini; antibakterijsko djelovanje; antimikotsko djelovanje

Hrčak ID: 16821

URI
https://hrcak.srce.hr/16821

[engleski]

Posjeta: 700 *