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Acta Pharmaceutica, Vol. 54 No. 2, 2004.

Kratko priopćenje

Phytochemical analysis of ethyl acetate extract from Astragalus corniculatus Bieb. and brain antihypoxic activity

ILINA KRASTEVA
IRINA NIKOLOVA
NICOLAY DANCHEV
STEFAN NIKOLOV

Puni tekst: engleski, pdf (60 KB) str. 151-156 preuzimanja: 1.397* citiraj
APA 6th Edition
KRASTEVA, I., NIKOLOVA, I., DANCHEV, N. i NIKOLOV, S. (2004). Phytochemical analysis of ethyl acetate extract from Astragalus corniculatus Bieb. and brain antihypoxic activity. Acta Pharmaceutica, 54 (2), 151-156. Preuzeto s https://hrcak.srce.hr/16826
MLA 8th Edition
KRASTEVA, ILINA, et al. "Phytochemical analysis of ethyl acetate extract from Astragalus corniculatus Bieb. and brain antihypoxic activity." Acta Pharmaceutica, vol. 54, br. 2, 2004, str. 151-156. https://hrcak.srce.hr/16826. Citirano 18.02.2019.
Chicago 17th Edition
KRASTEVA, ILINA, IRINA NIKOLOVA, NICOLAY DANCHEV i STEFAN NIKOLOV. "Phytochemical analysis of ethyl acetate extract from Astragalus corniculatus Bieb. and brain antihypoxic activity." Acta Pharmaceutica 54, br. 2 (2004): 151-156. https://hrcak.srce.hr/16826
Harvard
KRASTEVA, I., et al. (2004). 'Phytochemical analysis of ethyl acetate extract from Astragalus corniculatus Bieb. and brain antihypoxic activity', Acta Pharmaceutica, 54(2), str. 151-156. Preuzeto s: https://hrcak.srce.hr/16826 (Datum pristupa: 18.02.2019.)
Vancouver
KRASTEVA I, NIKOLOVA I, DANCHEV N, NIKOLOV S. Phytochemical analysis of ethyl acetate extract from Astragalus corniculatus Bieb. and brain antihypoxic activity. Acta Pharm. [Internet]. 2004 [pristupljeno 18.02.2019.];54(2):151-156. Dostupno na: https://hrcak.srce.hr/16826
IEEE
I. KRASTEVA, I. NIKOLOVA, N. DANCHEV i S. NIKOLOV, "Phytochemical analysis of ethyl acetate extract from Astragalus corniculatus Bieb. and brain antihypoxic activity", Acta Pharmaceutica, vol.54, br. 2, str. 151-156, 2004. [Online]. Dostupno na: https://hrcak.srce.hr/16826. [Citirano: 18.02.2019.]

Sažetak
Dry ethyl acetate extract containing flavonoids was obtained from above ground parts of Astragalus corniculatus Bieb. Seven flavonoids were isolated and identified as rutin, hyperoside, isoquercitrin, narcissin, quercetin, kaempferol and isorhamnetin for the first time. The extract was found to be practically non-toxic (acute oral toxicity > 5 g kg-1 in mice). The extract was investigated for antihypoxic activity in two models of experimental hypoxia - haemic and circulatory. Antihypoxic activity was especially pronounced in the model of circulatory hypoxia. This effect may be attributed, at least in part, to the presence of flavonoids in the extract.

Ključne riječi
Astragalus corniculatus Bieb. (Fabaceae); flavonoids; antihypoxic activity

Hrčak ID: 16826

URI
https://hrcak.srce.hr/16826

[hrvatski]

Posjeta: 1.906 *