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Cannabis in oncology

Ana Tečić Vuger   ORCID icon orcid.org/0000-0003-2203-161X ; Deparment of Medical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Robert Šeparović   ORCID icon orcid.org/0000-0002-4002-2699 ; Deparment of Medical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Tajana Silovski ; Deparment of Medical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Mirjana Pavlović ; Deparment of Medical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Vesna Pavlica ; Hospital Pharmacy, University Hospital for Tumors, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Sanda Vladimir Knežević ; Department of Pharmacognosy, Faculty of P harmacy, University of Zagreb, Croatia

Puni tekst: engleski, pdf (181 KB) str. 51-57 preuzimanja: 424* citiraj
APA 6th Edition
Tečić Vuger, A., Šeparović, R., Silovski, T., Pavlović, M., Pavlica, V. i Vladimir Knežević, S. (2016). Cannabis in oncology. Libri Oncologici, 44 (2-3), 51-57. Preuzeto s https://hrcak.srce.hr/177241
MLA 8th Edition
Tečić Vuger, Ana, et al. "Cannabis in oncology." Libri Oncologici, vol. 44, br. 2-3, 2016, str. 51-57. https://hrcak.srce.hr/177241. Citirano 26.01.2021.
Chicago 17th Edition
Tečić Vuger, Ana, Robert Šeparović, Tajana Silovski, Mirjana Pavlović, Vesna Pavlica i Sanda Vladimir Knežević. "Cannabis in oncology." Libri Oncologici 44, br. 2-3 (2016): 51-57. https://hrcak.srce.hr/177241
Harvard
Tečić Vuger, A., et al. (2016). 'Cannabis in oncology', Libri Oncologici, 44(2-3), str. 51-57. Preuzeto s: https://hrcak.srce.hr/177241 (Datum pristupa: 26.01.2021.)
Vancouver
Tečić Vuger A, Šeparović R, Silovski T, Pavlović M, Pavlica V, Vladimir Knežević S. Cannabis in oncology. Libri Oncologici [Internet]. 2016 [pristupljeno 26.01.2021.];44(2-3):51-57. Dostupno na: https://hrcak.srce.hr/177241
IEEE
A. Tečić Vuger, R. Šeparović, T. Silovski, M. Pavlović, V. Pavlica i S. Vladimir Knežević, "Cannabis in oncology", Libri Oncologici, vol.44, br. 2-3, str. 51-57, 2016. [Online]. Dostupno na: https://hrcak.srce.hr/177241. [Citirano: 26.01.2021.]

Sažetak
Although today among oncology patients use of various preparations of complementary and alternative medicine is more and more frequent, there is unequivocal scientifi c base for their use. Among the often used preparations, especially in the treatment of cancer pain, is cannabis and its derivatives. Cannabinoids act on the endogenous cannabinoid system, with widespread receptors in the central nervous system and peripheral tissues. Although the pharmacology of the cannabinoids is still largely unknown, numerous of their eff ects were investigated. In oncology, studies have been conducted on the effect
of cannabinoids on nausea and vomiting during the oncological treatment, the cancer pain and neuropathy, on appetite and weight loss, and the impact on mood, depression and anxiety. It is also observed that some of the cannabinoids have antitumor, but also protumorous activity. There have been many diff erent side eff ects of cannabinoids detected, and in a smaller percentage also the development of addiction. Best known preparations nowadays are dronabinol, nabilon and nabiximol. At the moment, the evidence lack strenght, and large randomized clinical trials are required, which would confi rm predominatly positive results of the research.

Ključne riječi
CAM; cannabis; cannabinoids; CB1; CB2; cancer pain; cancer cachexia; chemotherapy induced nausea and vomiting; adverse eff ects; anticancer activity; protumorous eff ect; dronabinol; nabilon; nabiximol

Hrčak ID: 177241

URI
https://hrcak.srce.hr/177241

[hrvatski]

Posjeta: 1.072 *