Skoči na glavni sadržaj

Chemical and Biochemical Engineering Quarterly, Vol. 31 No. 1, 2017.

Izvorni znanstveni članak

https://doi.org/10.15255/CABEQ.2016.952

Batch Cultivation Model for Biopolymer Production

C. E. Torres-Cerna orcid id orcid.org/0000-0001-5166-2408 ; CUCEI, Universidad de Guadalajara, Blvd. Marcelino Garcia Barragan 1421, Col. Olimpica, Guadalajara, Jalisco, México, C. P. 44430
A. Y. Alanis orcid id orcid.org/0000-0001-9600-779X ; CUCEI, Universidad de Guadalajara, Blvd. Marcelino Garcia Barragan 1421, Col. Olimpica, Guadalajara, Jalisco, México, C. P. 44430
I. Poblete-Castro ; Universidad Andrés Bello, Faculty of Biological Sciences, Center for Bioinformatics and Integrative Biology, Biosystems Engineering Laboratory, 8340176 Santiago, Chile
E. A. Hernandez-Vargas orcid id orcid.org/0000-0002-3645-435X ; c)Systems Medicine of Infectious Diseases, Helmholtz Centre for Infection Research, Inhoffenstr. 7, 38124 Braunschweig, Germany; d)Frankfurt Institute for Advanced Studies (FIAS), Ruth-Moufang-Str. 1, 60438 Frankfurt am Main, Germany

Puni tekst: engleski pdf 1.508 Kb

str. 89-99

preuzimanja: 812

citiraj

Sažetak

This paper presents a mathematical model to evaluate the kinetics of two different Pseudomonas putida strains, wild and mutant-type for the microbial production of polyhydroxyalkanoates (PHAs). Model parameters were estimated to represent adequately experimental data from the batch reactor using the differential evolution algorithm. Based on the mathematical model with the best-fit parameter values, simulations suggested that the high production of PHA by the mutant strain can be attributed not only to the higher production of PHA but also to a reduction in the consumption rate of the substrates of
approximately 66 %. Remarkably, the cell growth rate value is higher for the wild type than the mutant type, suggesting that the PHA increase is not only to an increase in the production rate but also to the metabolism of the cells. This mathematical model advances
comprehension of the PHA production capacity by P. putida paving the road towards environmentally friendly plastics.






This work is licensed under a Creative Commons Attribution 4.0 International License.

Ključne riječi

mathematical modeling; batch cultivation kinetics; biopolymers; Pseudomonas putida; polyhydroxyalkanoates

Hrčak ID:

179835

URI

https://hrcak.srce.hr/179835

Datum izdavanja:

13.4.2017.

Posjeta: 1.361 *