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The therapeutic effect of PAM-2 Cl on armin poisoned mice

Z. Binenfeld ; Institut za toksikologiju VMA, Beograd
V. Vojvodić ; Institut za toksikologiju VMA, Beograd
V. Božić ; Institut za toksikologiju VMA, Beograd

Puni tekst: srpski, pdf (8 MB) str. 207-217 preuzimanja: 59* citiraj
APA 6th Edition
Binenfeld, Z., Vojvodić, V. i Božić, V. (1961). Terapijski učinak PAM-2-hlorida na miševima otrovanim arminom. Arhiv za higijenu rada i toksikologiju, 12 (3-4), 207-217. Preuzeto s https://hrcak.srce.hr/182162
MLA 8th Edition
Binenfeld, Z., et al. "Terapijski učinak PAM-2-hlorida na miševima otrovanim arminom." Arhiv za higijenu rada i toksikologiju, vol. 12, br. 3-4, 1961, str. 207-217. https://hrcak.srce.hr/182162. Citirano 29.09.2020.
Chicago 17th Edition
Binenfeld, Z., V. Vojvodić i V. Božić. "Terapijski učinak PAM-2-hlorida na miševima otrovanim arminom." Arhiv za higijenu rada i toksikologiju 12, br. 3-4 (1961): 207-217. https://hrcak.srce.hr/182162
Harvard
Binenfeld, Z., Vojvodić, V., i Božić, V. (1961). 'Terapijski učinak PAM-2-hlorida na miševima otrovanim arminom', Arhiv za higijenu rada i toksikologiju, 12(3-4), str. 207-217. Preuzeto s: https://hrcak.srce.hr/182162 (Datum pristupa: 29.09.2020.)
Vancouver
Binenfeld Z, Vojvodić V, Božić V. Terapijski učinak PAM-2-hlorida na miševima otrovanim arminom. Arh Hig Rada Toksikol. [Internet]. 1961 [pristupljeno 29.09.2020.];12(3-4):207-217. Dostupno na: https://hrcak.srce.hr/182162
IEEE
Z. Binenfeld, V. Vojvodić i V. Božić, "Terapijski učinak PAM-2-hlorida na miševima otrovanim arminom", Arhiv za higijenu rada i toksikologiju, vol.12, br. 3-4, str. 207-217, 1961. [Online]. Dostupno na: https://hrcak.srce.hr/182162. [Citirano: 29.09.2020.]

Sažetak
PAM-2 Cl (pyridine-2-aldoxime methyl chloride) was obtained by allowing the solution of PAM-2 (pyridine-2-aldoxime methyl iodide) to pass through the anion exchanger Duolit A-30 or by boiling a saturated PAM-2 solution with AgCI. The yield was 35-50%, m. p. 218-220° C (uncor.), solubility in water 1:1. The concentration of 1.10-4 PAM-2 Cl produces a 25% inhibition of the rabbit's plasma and erythrocyte ChE. The concentration of 1.10-4 PAM-2 Cl produces, in an hour, 80% reactivation of the same enzymes inhibited by armin (ethyl-p-nitrophenyl ethylphosphonate). The same results were obtained with PAM-2. The protective effect of P AM-2 Cl on the mice poisoned by armin is equal to that of PAM-2 regarding both the dose and the time of application.

Hrčak ID: 182162

URI
https://hrcak.srce.hr/182162

[srpski]

Posjeta: 136 *