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Original scientific paper

Biochemical properties of some toxic proteins

N. Mujić ; Škola narodnog zdravlja »Andrija Štampar«, Medicinski fakultet Zagreb

Fulltext: croatian, pdf (27 MB) pages 1-30 downloads: 34* cite
APA 6th Edition
Mujić, N. (1959). O svojstvima nekih toksičnih proteina. Arhiv za higijenu rada i toksikologiju, 10 (1), 1-30. Retrieved from https://hrcak.srce.hr/183134
MLA 8th Edition
Mujić, N.. "O svojstvima nekih toksičnih proteina." Arhiv za higijenu rada i toksikologiju, vol. 10, no. 1, 1959, pp. 1-30. https://hrcak.srce.hr/183134. Accessed 15 Sep. 2019.
Chicago 17th Edition
Mujić, N.. "O svojstvima nekih toksičnih proteina." Arhiv za higijenu rada i toksikologiju 10, no. 1 (1959): 1-30. https://hrcak.srce.hr/183134
Harvard
Mujić, N. (1959). 'O svojstvima nekih toksičnih proteina', Arhiv za higijenu rada i toksikologiju, 10(1), pp. 1-30. Available at: https://hrcak.srce.hr/183134 (Accessed 15 September 2019)
Vancouver
Mujić N. O svojstvima nekih toksičnih proteina. Arh Hig Rada Toksikol. [Internet]. 1959 [cited 2019 September 15];10(1):1-30. Available from: https://hrcak.srce.hr/183134
IEEE
N. Mujić, "O svojstvima nekih toksičnih proteina", Arhiv za higijenu rada i toksikologiju, vol.10, no. 1, pp. 1-30, 1959. [Online]. Available: https://hrcak.srce.hr/183134. [Accessed: 15 September 2019]

Abstracts
The toxic proteins from Vip. ammodytes a. venom can be selectively adsorbed on filter paper fibers, so that antigenic composition of filtrated aqueous solution can be considered as changed. The water insoluble precipitate obtained from Vip. ammodyt. toxin can be purified by reprecipitation from aqueous solution at its isoelectric point. This substance shows the properties of a non-toxic pure protein. The Oudin test gives evidence for the presence of three precipitating antigenic components in the venom of Ammodytes viper. Six or seven protein components in crude venom can be distinguished by their different electrophoretic mobilities. The same value for immune serum has been obtained in the neutralization test of Vip. ammodytes toxin, irrespective of which of the activities of venom, haemolysis or toxicity in mice were used for indicating the endpoint. Thus the haemolytic and toxic effects of the venom can be considered as the properties of a single substance. The toxin-antitoxin precipitation curve was of the floculation type showing a maximum, corresponding to the neutralization point as revealed through the measurement of haemolytic activity of venom and antitoxic potency of antivenin. Six protein components with different electrophoretic mobilities can be distinguished when the venom of the spider Latrodectus tredecimguttatus Rossi is examined by electrophoresis. The immune serum against Latrodectus t. R. toxin was analysed electrophoretically.

Hrčak ID: 183134

URI
https://hrcak.srce.hr/183134

[croatian]

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