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CAUSES OF MORTALITY IN SCHIZOPHRENIA: AN UPDATED REVIEW OF EUROPEAN STUDIES

Patryk Piotrowski ; Department of Psychiatry, Wroclaw Medical University, Wroclaw, Poland
Tomasz M. Gondek orcid id orcid.org/0000-0002-5797-9972 ; Department of Psychiatry, Wroclaw Medical University, Wroclaw, Poland
Anna Królicka-Deręgowska ; Department of Psychiatry, Wroclaw Medical University, Wroclaw, Poland
Błażej Misiak ; Department of Genetics, Wroclaw Medical University, Wroclaw, Poland
Tomasz Adamowski ; Department of Nervous System Diseases, Faculty of Health Science, Wroclaw Medical University, Wroclaw, Poland
Andrzej Kiejna ; Institute of Psychology, University of Lower Silesia, Wroclaw, Poland


Puni tekst: engleski pdf 306 Kb

str. 108-120

preuzimanja: 1.619

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Sažetak

Background: The excess mortality in schizophrenia is still a phenomenon insufficiently studied on the cross-national level. It is
important to analyse current studies on morality in schizophrenia since significant changes have recently taken place in psychiatric
health care systems and guidelines of pharmacological treatment have been developed in European countries.
Subjects and methods: This article reviews studies addressing mortality in schizophrenia in Europe that were published in
English in the Pubmed database in 2009-2014. It aimed at determining countries where studies were conducted, methodologies and
tools used, and current main mortality rates, as well as direction of causality in this group of patients.
Results: The recently published studies were conducted only in few European countries. The majority of data was obtained from
general medical records and death records. The studies indicate that schizophrenia patients are characterized by higher mortality
rate than the general population, with natural causes (cardiovascular diseases and cancers) and suicides predominating. The
increasing mortality gap with significantly shorter life expectancy of patients with schizophrenia in comparison with the general
population is considerable.
Conclusions: Death records are a crucial tool in studies on mortality in schizophrenia patients; however they are insufficiently
employed. Recent European reports do not show positive tendencies, indicating that standardized mortality rates in schizophrenia
remain on the same level or even increase, particularly for deaths resulting from natural causes. Due to various methodologies used
in studies, their direct comparison is difficult. This limitation warrants further discussion on methods used in future studies on
schizophrenia mortality in Europe.

Ključne riječi

schizophrenia; mortality; life expectancy; epidemiology

Hrčak ID:

184431

URI

https://hrcak.srce.hr/184431

Datum izdavanja:

28.6.2017.

Posjeta: 2.050 *