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https://doi.org/10.32582/aa.58.1.8

Assessment of the effects of bisphenol-A as a disruptor on ionic regulation in Danio rerio zebrafish through a study of their chloride and prolactin cells

María I. BARASONA   ORCID icon orcid.org/0000-0001-6828-5100 ; Department of Pharmacology, Toxicology and Legal and Forensic Medicine. Veterinary Faculty. University of Córdoba, Campus de Rabanales Carretera Madrid-Cádiz s/n, Córdoba 14071, Spain
Ana MOLINA   ORCID icon orcid.org/0000-0002-2645-7303 ; Department of Pharmacology, Toxicology and Legal and Forensic Medicine. Veterinary Faculty. University of Córdoba, Campus de Rabanales Carretera Madrid-Cádiz s/n, Córdoba 14071, Spain
Alfonso BLANCO ; Department of Anatomy and ComDepartment of Anatomy and parative Pathology and Anatomy. Veterinary Faculty. University of Córdoba, Campus de Rabanales Carretera Madrid-Cádiz s/n, Córdoba 14071, Spain
Nahum AYALA ; Department of Pharmacology, Toxicology and Legal and Forensic Medicine. Veterinary Faculty. University of Córdoba, Campus de Rabanales Carretera Madrid-Cádiz s/n, Córdoba 14071, Spain
Rosario MOYANO ; Department of Pharmacology, Toxicology and Legal and Forensic Medicine. Veterinary Faculty. University of Córdoba, Campus de Rabanales Carretera Madrid-Cádiz s/n, Córdoba 14071, Spain

Puni tekst: engleski, pdf (1 MB) str. 105-115 preuzimanja: 387* citiraj
APA 6th Edition
BARASONA, M.I., MOLINA, A., BLANCO, A., AYALA, N. i MOYANO, R. (2017). Assessment of the effects of bisphenol-A as a disruptor on ionic regulation in Danio rerio zebrafish through a study of their chloride and prolactin cells. Acta Adriatica, 58 (1), 105-115. https://doi.org/10.32582/aa.58.1.8
MLA 8th Edition
BARASONA, María I., et al. "Assessment of the effects of bisphenol-A as a disruptor on ionic regulation in Danio rerio zebrafish through a study of their chloride and prolactin cells." Acta Adriatica, vol. 58, br. 1, 2017, str. 105-115. https://doi.org/10.32582/aa.58.1.8. Citirano 06.03.2021.
Chicago 17th Edition
BARASONA, María I., Ana MOLINA, Alfonso BLANCO, Nahum AYALA i Rosario MOYANO. "Assessment of the effects of bisphenol-A as a disruptor on ionic regulation in Danio rerio zebrafish through a study of their chloride and prolactin cells." Acta Adriatica 58, br. 1 (2017): 105-115. https://doi.org/10.32582/aa.58.1.8
Harvard
BARASONA, M.I., et al. (2017). 'Assessment of the effects of bisphenol-A as a disruptor on ionic regulation in Danio rerio zebrafish through a study of their chloride and prolactin cells', Acta Adriatica, 58(1), str. 105-115. https://doi.org/10.32582/aa.58.1.8
Vancouver
BARASONA MI, MOLINA A, BLANCO A, AYALA N, MOYANO R. Assessment of the effects of bisphenol-A as a disruptor on ionic regulation in Danio rerio zebrafish through a study of their chloride and prolactin cells. Acta Adriatica [Internet]. 2017 [pristupljeno 06.03.2021.];58(1):105-115. https://doi.org/10.32582/aa.58.1.8
IEEE
M.I. BARASONA, A. MOLINA, A. BLANCO, N. AYALA i R. MOYANO, "Assessment of the effects of bisphenol-A as a disruptor on ionic regulation in Danio rerio zebrafish through a study of their chloride and prolactin cells", Acta Adriatica, vol.58, br. 1, str. 105-115, 2017. [Online]. https://doi.org/10.32582/aa.58.1.8

Sažetak
Bisphenol A (BPA) is one of the chemicals produced in the largest volume in the world. It is commonly used as a component of plastics and food containers and can act as a xenoestrogen in humans. In view of the risk of exposure to it from the environment and diet, and basically as a water pollutant, the objective of our study was to assess possible effects on ionic regulation after exposure to BPA by means of a histopathological and morphometric study of the chloride and prolactin cells in zebrafish (Danio rerio) as an experimental model. Twenty-five male 16-week old zebrafish (Danio rerio) were allocated randomly into 5 study
groups (n=5/group); a control group, and four groups, exposed for 2 weeks to a concentration of (1, 10, 100 and 1000 μg/L) of BPA, respectively. After 2 weeks, the animals were sacrificed and samples
of their gills and pituitary gland were immediately taken for their subsequent histopathological analysis. Our results showed how, in the first study groups, lesions appeared in chloride cells, generating compensatory modifications in the prolactin cells, which were enough to maintain stability in the ionic exchange. As the exposure concentration increased, more serious histological modifications occurred. In the groups with the highest concentration (100 and 1000 μg/L), the lesions were so severe that the prolactin cells underwent some degenerative processes, which probably prevented the compensatory action at gill level.

Ključne riječi
Danio rerio; Bisphenol A; zebrafish; ionic regulation; prolactin cells; chloride cells

Hrčak ID: 185178

URI
https://hrcak.srce.hr/185178

[hrvatski]

Posjeta: 659 *