Infektološki glasnik, Vol. 27 No. 2, 2007.
Uvodnik
Viruses and apoptosis
M. Janković
A. Markotić
Sažetak
Apoptosis is an active process of cell death that doesn't initiate immune system response. Manipulation of the signalling cascades regulating apoptosis can result in a wide variety of human diseases. Viruses have the ability to affect the apoptotic process within the host cell. They can benefit either from the promotion or the inhibition of apoptosis. The benefits of virus avoiding the apoptotic process are obvious but the onset of apoptosis can also be advantageous. It enables the dissemination of virus without initiating a concomitant inflammatory host response. The purpose of this article was to give an overview of the mechanisms of apoptosis and examples for some of the many ways in which viruses and their gene products can influence this process. The progress of molecular biology has opened an era in which viral genes could be used for the production of different therapeutics.
Ključne riječi
Hrčak ID:
17840
URI
Datum izdavanja:
30.6.2007.
Posjeta: 2.505 *