Stručni rad

Some aspects of sexually transmitted diseases therapy

Ž. Šperanda
M. Halbauer

Sažetak

Diagnostic analysis, treatment and control were made in examinees with early symptoms of lower genital tract infections. The main symptoms were repeated itching around vulva as well as intensified prolonged secrete – discharge. The detection of C. trachomatis was done by the »Human« test based on monoclonal LPS antigens in reaction with LPS antibodies. Mycoplasmas were detected by »Mycoplasma duo« set produced by »Bio-Rad«. Aerobic bacteria were cultivated in aerobic conditions on standard media. Fungi, Trichomonas vaginalis and Gardnerella vaginalis infections were detected by PAPA test. The results showed that the four most frequent agents were C. trachomatis, then M. hominis and U. urealyticum and finally Trichomonas vaginalis.Therapy was administered according to treatment guidelines, with doxycycline in doses of 2×100 mg/21 days for both partners [1], azithromycin 3×500 mg per week [2] and roxithromycin 2×300 mg for three weeks [3]. T. vaginalis infections were treated with metronidazole 2×400 mg/7–10 days for both partners. The control cervical swab was taken after the four-week interval without any therapy. The results showed that examinees were cured in about 70 % cases after the first treatment against T. vaginalis and mycoplasma. The rest of 30 % were cured in the second therapy treatment. Unfortunately, the therapy of C. trachomatis wasn't so successful. We were monitoring clinical characteristics of the inflammation such as redness of vulva, vagina and cervicitis manifestation, intensified secrete and characteristic repeated discharge. Clinical symptoms of the inflammation disappeared mostly till the fourth control, except in a lesser number of cases. Also we made control cervical swabs for C. trachomatis. We repeated swab controls as long as the patient arrived to control because of disturbances, or the swab was positive in some cases nine times. Swabs tested for C. trachomatis became negative in only 36,8 % cases. The validity of such long treatment with apparently unfavorable results is controversal. On the other hand, examinees in whom clinical symptoms of illness ceased, experienced disease relapse in only a small number of cases. Complications were prevented, therefore it is our opinion that diagnostics and therapy have to be continued.

Ključne riječi

sexually transmitted diseases; therapy; antibiotics; C. trachomatis

Hrčak ID:

17900

URI

https://hrcak.srce.hr/17900

Datum izdavanja:

8.12.2005.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.644 *