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Original scientific paper
https://doi.org/10.20471/acc.2017.56.03.03

Sensitivity of Diagnostic Tests for Dry Eye in Patients with Blepharospasm

Dubravka Biuk ; Department of Ophthalmology, Osijek University Hospital Centre, School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia
Maja Vinković ; Department of Ophthalmology, Osijek University Hospital Centre, School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia
Suzana Matić ; Department of Ophthalmology, Osijek University Hospital Centre, School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia
Mario Bradvica ; Department of Ophthalmology, Osijek University Hospital Centre, School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia
Egon Biuk ; 2Department of Orthopedic Surgery, Osijek University Hospital Centre, School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia
Tvrtka Benašić ; Department of Ophthalmology, Osijek University Hospital Centre, School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia

Fulltext: english, pdf (113 KB) pages 375-381 downloads: 327* cite
APA 6th Edition
Biuk, D., Vinković, M., Matić, S., Bradvica, M., Biuk, E. & Benašić, T. (2017). Sensitivity of Diagnostic Tests for Dry Eye in Patients with Blepharospasm. Acta clinica Croatica, 56. (3.), 375-381. https://doi.org/10.20471/acc.2017.56.03.03
MLA 8th Edition
Biuk, Dubravka, et al. "Sensitivity of Diagnostic Tests for Dry Eye in Patients with Blepharospasm." Acta clinica Croatica, vol. 56., no. 3., 2017, pp. 375-381. https://doi.org/10.20471/acc.2017.56.03.03. Accessed 30 Jul. 2021.
Chicago 17th Edition
Biuk, Dubravka, Maja Vinković, Suzana Matić, Mario Bradvica, Egon Biuk and Tvrtka Benašić. "Sensitivity of Diagnostic Tests for Dry Eye in Patients with Blepharospasm." Acta clinica Croatica 56., no. 3. (2017): 375-381. https://doi.org/10.20471/acc.2017.56.03.03
Harvard
Biuk, D., et al. (2017). 'Sensitivity of Diagnostic Tests for Dry Eye in Patients with Blepharospasm', Acta clinica Croatica, 56.(3.), pp. 375-381. https://doi.org/10.20471/acc.2017.56.03.03
Vancouver
Biuk D, Vinković M, Matić S, Bradvica M, Biuk E, Benašić T. Sensitivity of Diagnostic Tests for Dry Eye in Patients with Blepharospasm. Acta clinica Croatica [Internet]. 2017 [cited 2021 July 30];56.(3.):375-381. https://doi.org/10.20471/acc.2017.56.03.03
IEEE
D. Biuk, M. Vinković, S. Matić, M. Bradvica, E. Biuk and T. Benašić, "Sensitivity of Diagnostic Tests for Dry Eye in Patients with Blepharospasm", Acta clinica Croatica, vol.56., no. 3., pp. 375-381, 2017. [Online]. https://doi.org/10.20471/acc.2017.56.03.03

Abstracts
The aim of the study was to evaluate diagnostic tests for keratoconjunctivitis sicca (Schirmer test, tear break-up time (TBUT) test, and corneal staining with fluorescein and lissamine green dye) in patients with blepharospasm. This prospective study included 60 female patients older than 40 with blepharospasm, divided into two groups according to clinical symptoms. For fluorescein test, the surface under the ROC curve was 1.0 with standard error (SE) 0 and 95% confidence interval (95% CI) 0.940-1.0; for Schirmer test, the surface under the ROC curve was 0.817 with SE 0.0555 and 95% CI 0.696-0.905; for lissamine green test, the surface under the ROC curve was 0.813 with SE 0.056 and 95% CI 0.691-0.902; and for TBUT test, the surface under the ROC curve was 0.772 with SE 0.061 and 95% CI 0.645-0.870. According to the results of ROC curve, which determines the sensitivity and specificity of normal values, comparison of diagnostic tests for keratoconjunctivitis sicca used in this study showed that fluorescein test had the best sensitivity and specificity. Schirmer test should be avoided in patients with blepharospasm because its results are influenced by frequent blinking and are not appropriate for study interpretation. Despite the pathologic values of TBUT test (numerically), this test is still acceptable for patients with blepharospasm because its interval takes more time than the interval between two blinks.

Keywords
Staining and labeling; Blepharospasm, Fluorescein; Lissamine green dye; ROC curve; Croatia

Hrčak ID: 191339

URI
https://hrcak.srce.hr/191339

[croatian]

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