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Review article
https://doi.org/10.20471/acc.2017.56.03.19

Jetrena osteodistrofija: globalni pre(po)gled problema

Ecaterina-Constanța Barbu ; Carol Davila University of Medicine and Pharmacy, Matei Balş National Institute for Infectious Diseases, I. Cantacuzino Clinical Hospital, Bucharest, Romania
Cristina-Emilia Chițu-Tișu ; Carol Davila University of Medicine and Pharmacy, Matei Balş National Institute for Infectious Diseases, I. Cantacuzino Clinical Hospital, Bucharest, Romania
Mihai Lazăr ; Carol Davila University of Medicine and Pharmacy, Matei Balş National Institute for Infectious Diseases
Cristina Olariu ; Carol Davila University of Medicine and Pharmacy, Matei Balş National Institute for Infectious Diseases
Mihai Bojincă ; Carol Davila University of Medicine and Pharmacy, I. Cantacuzino Clinical Hospital, Colentina Clinical Hospital, Bucharest, Romania
Răzvan Adrian Ionescu ; Carol Davila University of Medicine and Pharmacy, Colentina Clinical Hospital, Bucharest, Romania
Daniela Adriana Ion ; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Ioana Anca Bădărău ; Carol Davila University of Medicine and Pharmacy, Bucharest, Romani

Fulltext: english, pdf (141 KB) pages 512-525 downloads: 523* cite
APA 6th Edition
Barbu, E., Chițu-Tișu, C., Lazăr, M., Olariu, C., Bojincă, M., Adrian Ionescu, R., ... Anca Bădărău, I. (2017). Hepatic Osteodystrophy: A Global (Re)View of the Problem. Acta clinica Croatica, 56. (3.), 512-525. https://doi.org/10.20471/acc.2017.56.03.19
MLA 8th Edition
Barbu, Ecaterina-Constanța, et al. "Hepatic Osteodystrophy: A Global (Re)View of the Problem." Acta clinica Croatica, vol. 56., no. 3., 2017, pp. 512-525. https://doi.org/10.20471/acc.2017.56.03.19. Accessed 30 Jul. 2021.
Chicago 17th Edition
Barbu, Ecaterina-Constanța, Cristina-Emilia Chițu-Tișu, Mihai Lazăr, Cristina Olariu, Mihai Bojincă, Răzvan Adrian Ionescu, Daniela Adriana Ion and Ioana Anca Bădărău. "Hepatic Osteodystrophy: A Global (Re)View of the Problem." Acta clinica Croatica 56., no. 3. (2017): 512-525. https://doi.org/10.20471/acc.2017.56.03.19
Harvard
Barbu, E., et al. (2017). 'Hepatic Osteodystrophy: A Global (Re)View of the Problem', Acta clinica Croatica, 56.(3.), pp. 512-525. https://doi.org/10.20471/acc.2017.56.03.19
Vancouver
Barbu E, Chițu-Tișu C, Lazăr M, Olariu C, Bojincă M, Adrian Ionescu R, et al. Hepatic Osteodystrophy: A Global (Re)View of the Problem. Acta clinica Croatica [Internet]. 2017 [cited 2021 July 30];56.(3.):512-525. https://doi.org/10.20471/acc.2017.56.03.19
IEEE
E. Barbu, et al., "Hepatic Osteodystrophy: A Global (Re)View of the Problem", Acta clinica Croatica, vol.56., no. 3., pp. 512-525, 2017. [Online]. https://doi.org/10.20471/acc.2017.56.03.19

Abstracts
Jetrena osteodistrofi ja je česta i nerijetko neliječena komplikacija koja se manifestira kao osteoporoza ili osteopenija, a susreće se u bolesnika s kroničnim bolestima jetre. Ovaj narativni pregled jetrene osteodistrofi je preispituje učestalost, patofiziologiju, dijagnostiku i liječenje jetrene osteodistrofi je. Proveli smo pretragu medicinske literature u bazama podataka PubMed, Google Scholar, Wiley, Science Direct i Springer Link pomoću prikladnih ključnih riječi kako bismo dobili podatke o niskoj mineralnoj gustoći kosti povezanoj s kroničnim bolestima jetre. Mnoga istraživanja izvještavaju o povećanoj učestalosti osteoporoze/osteopenije u bolesnika s kroničnim jetrenim bolestima. Patogeneza je multifaktorijalna i uključuje genetske čimbenike, pomanjkanje raznih vitamina, proupalne citokine, hipogonadizam, hiperbilirubinemiju, protuvirusnu terapiju, kortikosteroidne lijekove te čimbenike povezane s načinom života. Liječenje ovih bolesnika treba obuhvatiti individualiziranu procjenu čimbenika rizika za prijelome te mineralnu gustoću kosti. Svim bolesnicima s kroničnim bolestima jetre i osteoporozom treba preporučiti uzimanje dodataka vitamina C i kalcija. Bisfosfonati su najučinkovitiji lijekovi za liječenje jetrene osteodistrofi je. Potrebno je bolje defi nirati zbrinjavanje i specifi čno liječenje jetrene osteodistrofi je kako bi se sprije čili prijelomi zbog krhkih kosti te poboljšala kvaliteta života ovih bolesnika.

Keywords
Koštane bolesti, metaboličke – dijagnostika; Koštane bolesti, metaboličke – patofi ziologija; Osteoporoza, Prijelomi kosti; Bisfosfonati

Hrčak ID: 191667

URI
https://hrcak.srce.hr/191667

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