Medicinski vjesnik, Vol. 30 No. (1-2), 1998.
Stručni rad
Our experience in the long-term follow-up and treatment of a family with MEN 2A (2) syndrome
Juraj Smoje
Nedeljko Topuzović
Aleksandar Rusić
Jasna Gardašanić
Branislav Krstonošić
Ivan Karner
Sažetak
The effects of early treatment of the disease were studied in a 15-year study of the members of a family with MEN 2A syndrome. Twenty members of the family were followed-up during that period. Total thyreidectomy was performed in nine members and bilateral adrenalectomy due to pheochromocytoma in one. The mean age of operated persons was 25.1 years (16-41 year). Medullary thyroid was established in six patients and C-cell hyperplasia in three patients. A higher calcitonine level, without any evidence of metastases, has persisted in one female patient only. Calcitonine levels were measured after stimulation with pentagastrine and alcohol (vodka). It is our opinion that calcitonine stimulation with alcohol is still an appropriate and satisfying method. Any parathyroid disease has been established in none of twenty relatives.
Ključne riječi
multiple endocrine neoplasia 2A (MEN 2A)
Hrčak ID:
192068
URI
Datum izdavanja:
1.12.1998.
Posjeta: 1.072 *