hrcak mascot   Srce   HID

Izvorni znanstveni članak

The Homologation of 1-(2,3-Dihydroxypropyl)- into 1-(2,4-Dihydroxyhutyl)-thymine

V . Škarić ; Laboratory of Stereochemistry and Natural Products, »Ruder Boskovic« Institute, 41001 Zagreb, Croatia, Yugoslavia
Z. Raza ; Laboratory of Stereochemistry and Natural Products, »Ruder Boskovic« Institute, 41001 Zagreb, Croatia, Yugoslavia

Puni tekst: engleski, pdf (5 MB) str. 51-59 preuzimanja: 49* citiraj
APA 6th Edition
Škarić, V. i Raza, Z. (1979). The Homologation of 1-(2,3-Dihydroxypropyl)- into 1-(2,4-Dihydroxyhutyl)-thymine. Croatica Chemica Acta, 52 (1), 51-59. Preuzeto s https://hrcak.srce.hr/195914
MLA 8th Edition
Škarić, V . i Z. Raza. "The Homologation of 1-(2,3-Dihydroxypropyl)- into 1-(2,4-Dihydroxyhutyl)-thymine." Croatica Chemica Acta, vol. 52, br. 1, 1979, str. 51-59. https://hrcak.srce.hr/195914. Citirano 08.03.2021.
Chicago 17th Edition
Škarić, V . i Z. Raza. "The Homologation of 1-(2,3-Dihydroxypropyl)- into 1-(2,4-Dihydroxyhutyl)-thymine." Croatica Chemica Acta 52, br. 1 (1979): 51-59. https://hrcak.srce.hr/195914
Harvard
Škarić, V., i Raza, Z. (1979). 'The Homologation of 1-(2,3-Dihydroxypropyl)- into 1-(2,4-Dihydroxyhutyl)-thymine', Croatica Chemica Acta, 52(1), str. 51-59. Preuzeto s: https://hrcak.srce.hr/195914 (Datum pristupa: 08.03.2021.)
Vancouver
Škarić V, Raza Z. The Homologation of 1-(2,3-Dihydroxypropyl)- into 1-(2,4-Dihydroxyhutyl)-thymine. Croatica Chemica Acta [Internet]. 1979 [pristupljeno 08.03.2021.];52(1):51-59. Dostupno na: https://hrcak.srce.hr/195914
IEEE
V. Škarić i Z. Raza, "The Homologation of 1-(2,3-Dihydroxypropyl)- into 1-(2,4-Dihydroxyhutyl)-thymine", Croatica Chemica Acta, vol.52, br. 1, str. 51-59, 1979. [Online]. Dostupno na: https://hrcak.srce.hr/195914. [Citirano: 08.03.2021.]

Sažetak
The homologation of 1-(2,3-dihydroxypropyl)thymine involved
the conversion of its 3'-0-tosyl derivative II into the corresponding
3'-iodo compound IV, which by nucleophilic displacement with
sodium cy,anide in DMSO formed 1-(2-hydroxy-3-cyanopropyl)
thymine (VIII). 1-(2,3-Dihydroxypropyl)uracil was analogously converted
into the corresponding 3'-iodo- III and 3'-cyano- VII propyluracil.
The ethanolysis of the 3'-cyano compound VIII to 1-(2-
-hydroxy-3-ethoxycarbonylpropyl)thymine (X), followed by the
reduction with LiAlH4, gave 1-(2,4-dihydroxybutyl)thymine (XIII).
3'-0-Acetylthymidylyl(5'~2')-1-(4-0-triphenylmethyl-2,4-dihydroxybutyl)
thymine was described as possible N,N-dicyclohexylpseudourea
adduct XIX.

Hrčak ID: 195914

URI
https://hrcak.srce.hr/195914

Posjeta: 98 *