Croatica Chemica Acta, Vol. 51 No. 2, 1978.
Kratko priopćenje
The Synthesis of the Fluorescence Probe, 12-(1-Pyrenyl)dodecanoic Acid
B. Katušin-Ražem
; Radiation Laboratory, University of Notre Dame, Notre Dame, Indiana 46556, U .S.A.
Sažetak
The synthesis of the fluorescence probe, 12-(1-pyrenyl)dodecanoic
acid, was accomplished by the Wittig reaction between 1-
-pyrenecarboxaldehyde and 10-methoxycarbonyldecyltriphenylphosphonium
bromide, followed by hydrogenation of the unsaturated
product and hydrolysis of methyl ester. The Wittig reaction was
carried out with sodium methoxide in dimethylformamide, at room
temperature and under a N2 atmosphere. This reacion yielded a
mixture of 530/o trans .and 47-0/0 cis isomers of 12- (l-pyrenyl)-11-
-dodecenoate, as determined . by pulsed Fourier transform NMR
technique.
Ključne riječi
Hrčak ID:
195966
URI
Datum izdavanja:
26.9.1978.
Posjeta: 464 *