Medicinski vjesnik, Vol. 22 No. (4), 1990.
Stručni rad
Horton's disease with a special review of the giant-cell temporal arteritis
Miladin Štriga
Ivo Bonić
Drago De Syo
Stanko Stipetić
Zlatko Balog
Sažetak
The authors performed a retrospective study of 66 patients with Horton’s disease, of whom 20 (30.2%) had pathohistologically verified giant-cell temporal arteritis. Bitemporal biopsy was performed regularly, following the continuated bidirectional Doppler’s sonography of the carotid flow and ophthalmic artery. Ophthalmological signs of Horton’s disease were manifest as an anterior ishemic opticoneuropathy in 17 eyes (85 %), as a retrobulbar opticoneuropathy in two eyes (10 %) and as the occlusion of the central retinal artery in one eye (5 %). The most important and pathognomonic laboratory findings were an increased erythrocyte sedimentation rate (60 — 125 mm) and hyperleucocytosis. In 14 patients (70%) the signs of anemia were found: two thirds of them had a normochromic and one third a hyperchromic anemia. Serum values of IgA, IgG, IgM, C3 and C4 were somewhat increased inpatients with giant-cell arteritis as compared to the patients with idiopathic neuropathy, but with no significant aberrations, so that the observed findings cannot be relied upon in the differential diagnosis. All 20 patients with temporal arteritis suffered from a sudden deterioration or the loss of vision, ranging between 0.34 ± 0.8 before the treatment. After 14 months to two years of cortico-therapy according to a well-defined scheme, the vision improved slowly and ranged between 0.51 ± 0.7. As for the non-ophthalmological symptoms observed in our patients, 55 % of them had neuropsychiatric attacks, whereas rheumatic polymyalgia occured in 50 % of them.
Ključne riječi
giant-cell temporal arteritis; Horton’s disease
Hrčak ID:
196288
URI
Datum izdavanja:
1.12.1990.
Posjeta: 2.119 *