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Preliminary communication

Isotope Effects in the Photosensitized Dimerization of Pyrimidines

A. Kornhauser ; Harvard School of Dental Medicine, Boston, Mass. 02115
J. B. Burnett ; Harvard School of Dental Medicine, Boston, Mass. 02115
G. Szabo ; Institute »Ruder Boskovic«, 41000 .Zagreb,. Croatia, Yugoslavia

Fulltext: english, pdf (4 MB) pages 193-197 downloads: 51* cite
APA 6th Edition
Kornhauser, A., Burnett, J.B. & Szabo, G. (1974). Isotope Effects in the Photosensitized Dimerization of Pyrimidines. Croatica Chemica Acta, 46 (3), 193-197. Retrieved from https://hrcak.srce.hr/196815
MLA 8th Edition
Kornhauser, A., et al. "Isotope Effects in the Photosensitized Dimerization of Pyrimidines." Croatica Chemica Acta, vol. 46, no. 3, 1974, pp. 193-197. https://hrcak.srce.hr/196815. Accessed 21 Apr. 2021.
Chicago 17th Edition
Kornhauser, A., J. B. Burnett and G. Szabo. "Isotope Effects in the Photosensitized Dimerization of Pyrimidines." Croatica Chemica Acta 46, no. 3 (1974): 193-197. https://hrcak.srce.hr/196815
Harvard
Kornhauser, A., Burnett, J.B., and Szabo, G. (1974). 'Isotope Effects in the Photosensitized Dimerization of Pyrimidines', Croatica Chemica Acta, 46(3), pp. 193-197. Available at: https://hrcak.srce.hr/196815 (Accessed 21 April 2021)
Vancouver
Kornhauser A, Burnett JB, Szabo G. Isotope Effects in the Photosensitized Dimerization of Pyrimidines. Croatica Chemica Acta [Internet]. 1974 [cited 2021 April 21];46(3):193-197. Available from: https://hrcak.srce.hr/196815
IEEE
A. Kornhauser, J.B. Burnett and G. Szabo, "Isotope Effects in the Photosensitized Dimerization of Pyrimidines", Croatica Chemica Acta, vol.46, no. 3, pp. 193-197, 1974. [Online]. Available: https://hrcak.srce.hr/196815. [Accessed: 21 April 2021]

Abstracts
Many of the biological effects of ultraviolet radiation can be explained
in terms of specific chemical and physical changes in the DNA. Correlations
have been made between the survival of u. v. irradiated cells and the production of certain types of lesions in the DNA.1 The pyrimidines in the DNA are the most sensitive receptors of u. v. photons. Both in vitro and in vivo irradiation of DNA with u. v. light of wavelenghs shorter than 300 nm yield cyclobutyl pyrimidine dimeirs. Pyrimidines can also be dimerized with wavelengths longer than 300 nm in the presence of carbonyl compounds by means of energy tr:msfer.2,3,4,5 This pro_cess ~s known as molecular photosensitization and yields
exclusively dimers without concomitant photohydration. Molecula.r photosensitization is of fundamental biologic importance, as wavelengths longer than 300 nm are .present in the sun spectrum on the earth's surface.

Hrčak ID: 196815

URI
https://hrcak.srce.hr/196815

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