Stručni rad

Clinical spectrum of the adult onset still's disease

Ivan Zgradić

Sažetak

The paper presents clinical features of the adult onset Still’s disease, occurring in 12 adult patients (10 men and 2 women). All patients have satisfied ARA and recently adopted EULAR criteria as well as WHO criteria set in Oslo in 1977. That is, all of them developed the disease after the age 16 in the form of arthritis (polyarthritis, oligo- or monoarthritis). A prolonged febrile state (more frequently of the intermittent type) occurred in 11 patients, whereas 8 showed skin manifestations and 6 suffered from lymphadenopathy. Nine patients had splenomegaly and only 3 had hepatomegaly. Carditis occurred in two and polyserositis in four patients. A tendency to spontaneous remissions and recurrences was present in 11 patients. All 12 patients had positive non-specific reactions of the acute inflammatory phase. Leukocytosis and thrombocytosis were manifest in 10 patients, respectively. Alkalyne phosphatase was increased in 8 patients and the test for rheumatoid factors was negative in as many as ten. Depending upon the pathological findings, the patients were initially treated with non-steroid antirheumatic agents (NSAA), antibiotics, chloroquine and immunosuppressive agents; their effect was different in each case.

Ključne riječi

Still’s disease; adult

Hrčak ID:

196964

URI

https://hrcak.srce.hr/196964

Datum izdavanja:

1.12.1989.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.921 *