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Role of cytology in detection and treatment of breast tumors

Vesna Ramljak ; Department for Cytology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Iva Bobuš Kelčec ; Department for Cytology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Merdita Agai Muhaxhiri ; Department for Cytology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia

Puni tekst: engleski, pdf (288 KB) str. 15-22 preuzimanja: 147* citiraj
APA 6th Edition
Ramljak, V., Bobuš Kelčec, I. i Agai Muhaxhiri, M. (2014). Role of cytology in detection and treatment of breast tumors. Libri Oncologici, 42 (1-3), 15-22. Preuzeto s https://hrcak.srce.hr/199013
MLA 8th Edition
Ramljak, Vesna, et al. "Role of cytology in detection and treatment of breast tumors." Libri Oncologici, vol. 42, br. 1-3, 2014, str. 15-22. https://hrcak.srce.hr/199013. Citirano 26.01.2021.
Chicago 17th Edition
Ramljak, Vesna, Iva Bobuš Kelčec i Merdita Agai Muhaxhiri. "Role of cytology in detection and treatment of breast tumors." Libri Oncologici 42, br. 1-3 (2014): 15-22. https://hrcak.srce.hr/199013
Harvard
Ramljak, V., Bobuš Kelčec, I., i Agai Muhaxhiri, M. (2014). 'Role of cytology in detection and treatment of breast tumors', Libri Oncologici, 42(1-3), str. 15-22. Preuzeto s: https://hrcak.srce.hr/199013 (Datum pristupa: 26.01.2021.)
Vancouver
Ramljak V, Bobuš Kelčec I, Agai Muhaxhiri M. Role of cytology in detection and treatment of breast tumors. Libri Oncologici [Internet]. 2014 [pristupljeno 26.01.2021.];42(1-3):15-22. Dostupno na: https://hrcak.srce.hr/199013
IEEE
V. Ramljak, I. Bobuš Kelčec i M. Agai Muhaxhiri, "Role of cytology in detection and treatment of breast tumors", Libri Oncologici, vol.42, br. 1-3, str. 15-22, 2014. [Online]. Dostupno na: https://hrcak.srce.hr/199013. [Citirano: 26.01.2021.]

Sažetak
Fine-needle aspiration cytology (FNAC) is an established, highly accurate, and cost-eff ective method for diagnosing lesions in the breast. The method is minimally invasive without unwanted side efect. FNAC forms part of the triple assessment of breast lesions and has a high accuracy and sensitivity in dedicated centres. Method as a part of triple assessment has provide its value in describing the fi ndings most accurately. The diagnostic impact depends on experience of the operator, quality of preparation and diagnostic skills of the cytopathologist. Inadequate sampling with FNAC is particulary seen in
collagenous lesions and in submitt ed specimens sampled by physicians lacking experience with the FNAC procedure. The highest accuracy is achived at centres with multidisciplinary approach.
The majority of European countries use similar reporting system for breast FNAC (C1-C5), in keeping with European guidelines for quality assurance in breast cancer screening and diagnosis. A clear reporting system ensures that an unequivocal cytological diagnosis of malignancy is reliable, and in cases where mammography/ultrasonography and clinical examination are in agreement with FNAC, frozen section examination is unnecessary.
The issue of optimal sampling to obtain adequate cell material in suffi cient quantity is of paramount importance when assessing the accuracy of FNAC. The inadequate rates in FNAC from diff erent sources are lowest when FNAC is performed by a cytopathologist and highest when done by a non-cytopathologist. The multidisciplinary approach is necessary to amplify FNAC quality and to reduce its diagnostic limits. Only when this model of activity is not available, the role of FNAC
is less eff ective and the addition of core biopsy (CB) to FNAC should be considered. CB as an alternative diagnostic modality should be used advisedly, in situations where it is more likely to yield diagnostic information, e.g., in the diagnosis of impalpable masses, microcalcifi cations or a clinically apparent malignancy where preoperative chemotherapy is planned. CB should not be used as a substitute for poor performance at FNAC. The methods are not mutually exclusive.

Ključne riječi
breast; aspiration cytology; breast tumors; diagnosis

Hrčak ID: 199013

URI
https://hrcak.srce.hr/199013

[hrvatski]

Posjeta: 271 *