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Methotrexate – the Gold Standard in Rheumatology

Iva Žagar

Puni tekst: hrvatski, pdf (100 KB) str. 95-100 preuzimanja: 4.091* citiraj
APA 6th Edition
Žagar, I. (2018). Metotreksat – zlatni standard u reumatologiji. Medicus, 27 (1 Debljina i ...), 95-100. Preuzeto s https://hrcak.srce.hr/199425
MLA 8th Edition
Žagar, Iva. "Metotreksat – zlatni standard u reumatologiji." Medicus, vol. 27, br. 1 Debljina i ..., 2018, str. 95-100. https://hrcak.srce.hr/199425. Citirano 16.07.2020.
Chicago 17th Edition
Žagar, Iva. "Metotreksat – zlatni standard u reumatologiji." Medicus 27, br. 1 Debljina i ... (2018): 95-100. https://hrcak.srce.hr/199425
Harvard
Žagar, I. (2018). 'Metotreksat – zlatni standard u reumatologiji', Medicus, 27(1 Debljina i ...), str. 95-100. Preuzeto s: https://hrcak.srce.hr/199425 (Datum pristupa: 16.07.2020.)
Vancouver
Žagar I. Metotreksat – zlatni standard u reumatologiji. Medicus [Internet]. 2018 [pristupljeno 16.07.2020.];27(1 Debljina i ...):95-100. Dostupno na: https://hrcak.srce.hr/199425
IEEE
I. Žagar, "Metotreksat – zlatni standard u reumatologiji", Medicus, vol.27, br. 1 Debljina i ..., str. 95-100, 2018. [Online]. Dostupno na: https://hrcak.srce.hr/199425. [Citirano: 16.07.2020.]

Sažetak
Methotrexate (MTX) is a structural analogue of folic acid which is used primarily to treat inMammatory rheumatic diseases, with oral or parenteral administration. The efficacy of MTX in the treatment of rheumatoid arthritis has been demonstrated in several randomized clinical studies and conformed in meta-analyses. Today, MTX represents the golden standard for the treatment of rheumatoid arthritis. The treatment starts at doses between 7.5 and 15 mg per week, with possible dose escalation based on disease activity. Careful patient monitoring reduces the risk of hepatotoxicity and other adverse effects, making MTX the drug of first choice for the treatment of rheumatoid and psoriatic arthritis.

Ključne riječi
methotrexate; rheumatoid arthritis; psoriatic arthritis

Hrčak ID: 199425

URI
https://hrcak.srce.hr/199425

[hrvatski]

Posjeta: 4.269 *