Biochemia Medica, Vol. 28 No. 2, 2018.
Izvorni znanstveni članak
https://doi.org/10.11613/BM.2018.020711
Comparison between Sigma metrics in four accredited Egyptian medical laboratories in some biochemical tests: an initiative towards sigma calculation harmonization
Rania El Sharkawy
; Medical Research Institute, Alexandria University, Alexandria, Egypt
Sten Westgard
; Westgard QC Inc., Madison, USA
Ahmed M Awad
; Medical Research Institute, Alexandria University, Alexandria, Egypt
AbdelKarem Omneya I Ahmed
; Medical Research Institute, Alexandria University, Alexandria, Egypt
El Hadidi Iman
; Ain Shams University, Cairo, Egypt
Ahmed Gaballah
; Zagazig University, Zagazig, Egypt
Eman Shaheen
; Private laboratory, Helwan University, Alexandria, Egypt
Sažetak
Introduction: Analytical quality is an essential requirement for best practice in any medical laboratory. Lack of a harmonized approach for sigma
calculation is considered an obstacle in the objective comparability of analytical performance among laboratories adopting sigma metrics. It is
urgently needed that all laboratory professionals interested in the analytical quality to work hard towards harmonization protocol for sigma calculation
in order to properly select their analytical goals. This study aims at harmonization of Sigma metrics calculation in four accredited Egyptian
laboratories.
Materials and methods: This observational cross sectional study compared the sigma levels for certain biochemical parameters in the four participating
laboratories.
Results: Coefficient of variation (CV) and bias were determined for some biochemical analytes, data assayed by different automated analysers in
the four different accredited laboratories. The sigma level for the four medical laboratories was calculated for each biomedical parameter with changed
sigma level after total allowable error (Tea) unification among participating laboratories.
Conclusion: Each laboratory should select the TEa goal based on clear standardized criteria of selection without any subjective preferences as either
under or over estimation of Sigma metrics will affect the patient centred care negatively if laboratories use quality control procedures wrongly based
on incorrect Sigma metrics calculation with subsequent misleading medical decisions.
Ključne riječi
sigma; bias; coefficient of variation; harmonization; total allowable error
Hrčak ID:
201531
URI
Datum izdavanja:
15.6.2018.
Posjeta: 1.239 *