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Food Technology and Biotechnology, Vol.56 No.2 Lipanj 2018.

Prethodno priopćenje
https://doi.org/10.17113/ftb.56.02.18.5474

The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation

Andrea Antolić ; University of Zagreb, Faculty of Science, Roosevelt Square 6, HR- 10000 Zagreb, Croatia
Željan Maleš ; University of Zagreb, Faculty of Pharmacy and Biochemistry, Department of Pharmaceutical Botany, Schrottova 39, HR-10000 Zagreb, Croatia
Maja Tomičić ; Croatian Institute of Transfusion Medicine, Department of Platelet and Leukocyte Immunology, Petrova 6, HR-10000 Zagreb, Croatia
Mirza Bojić ; University of Zagreb, Faculty of Pharmacy and Biochemistry, Department of Medicinal Chemistry, A. Kovačića 1, HR-10000 Zagreb, Croatia

Puni tekst: engleski, pdf (164 KB) str. 265-269 preuzimanja: 0* citiraj
APA 6th Edition
Antolić, A., Maleš, Ž., Tomičić, M. i Bojić, M. (2018). The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation. Food Technology and Biotechnology, 56 (2), 265-269. https://doi.org/10.17113/ftb.56.02.18.5474
MLA 8th Edition
Antolić, Andrea, et al. "The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation." Food Technology and Biotechnology, vol. 56, br. 2, 2018, str. 265-269. https://doi.org/10.17113/ftb.56.02.18.5474. Citirano 22.07.2018.
Chicago 17th Edition
Antolić, Andrea, Željan Maleš, Maja Tomičić i Mirza Bojić. "The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation." Food Technology and Biotechnology 56, br. 2 (2018): 265-269. https://doi.org/10.17113/ftb.56.02.18.5474
Harvard
Antolić, A., et al. (2018). 'The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation', Food Technology and Biotechnology, 56(2), str. 265-269. doi: https://doi.org/10.17113/ftb.56.02.18.5474
Vancouver
Antolić A, Maleš Ž, Tomičić M, Bojić M. The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation. Food Technology and Biotechnology [Internet]. 29.06.2018. [pristupljeno 22.07.2018.];56(2):265-269. doi: https://doi.org/10.17113/ftb.56.02.18.5474
IEEE
A. Antolić, Ž. Maleš, M. Tomičić i M. Bojić, "The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation", Food Technology and Biotechnology, vol.56, br. 2, str. 265-269, Srpanj 2018. [Online]. doi: https://doi.org/10.17113/ftb.56.02.18.5474
Puni tekst: hrvatski, pdf (164 KB) str. 265-269 preuzimanja: 0* citiraj
APA 6th Edition
Antolić, A., Maleš, Ž., Tomičić, M. i Bojić, M. (2018). Učinak ekstrakata kratkozupčaste i dalmatinske kadulje na agregaciju trombocita. Food Technology and Biotechnology, 56 (2), 265-269. https://doi.org/10.17113/ftb.56.02.18.5474
MLA 8th Edition
Antolić, Andrea, et al. "Učinak ekstrakata kratkozupčaste i dalmatinske kadulje na agregaciju trombocita." Food Technology and Biotechnology, vol. 56, br. 2, 2018, str. 265-269. https://doi.org/10.17113/ftb.56.02.18.5474. Citirano 22.07.2018.
Chicago 17th Edition
Antolić, Andrea, Željan Maleš, Maja Tomičić i Mirza Bojić. "Učinak ekstrakata kratkozupčaste i dalmatinske kadulje na agregaciju trombocita." Food Technology and Biotechnology 56, br. 2 (2018): 265-269. https://doi.org/10.17113/ftb.56.02.18.5474
Harvard
Antolić, A., et al. (2018). 'Učinak ekstrakata kratkozupčaste i dalmatinske kadulje na agregaciju trombocita', Food Technology and Biotechnology, 56(2), str. 265-269. doi: https://doi.org/10.17113/ftb.56.02.18.5474
Vancouver
Antolić A, Maleš Ž, Tomičić M, Bojić M. Učinak ekstrakata kratkozupčaste i dalmatinske kadulje na agregaciju trombocita. Food Technology and Biotechnology [Internet]. 29.06.2018. [pristupljeno 22.07.2018.];56(2):265-269. doi: https://doi.org/10.17113/ftb.56.02.18.5474
IEEE
A. Antolić, Ž. Maleš, M. Tomičić i M. Bojić, "Učinak ekstrakata kratkozupčaste i dalmatinske kadulje na agregaciju trombocita", Food Technology and Biotechnology, vol.56, br. 2, str. 265-269, Srpanj 2018. [Online]. doi: https://doi.org/10.17113/ftb.56.02.18.5474

Sažetak
Sage (Salvia sp.) is a genus of a native Mediterranean plant used for aromatization of foods. In this study, total polyphenolic profile, antioxidant properties and antiplatelet effect of short-toothed sage (Salvia brachyodon Vandas) are analyzed and compared to most commonly used Salvia species (S. officinalis, Dalmatian sage). Content of total flavonoids was 0.08-0.23 % and of phenolic acids 0.47-3.04 %. Antioxidant DPPH assay showed higher antioxidant capacity of S. brachyodon (29-36 mg/mL of gallic acid equivalents) than of S. officinalis. In functional test of primary haemostasis, extracts of S. brachyodon have prevented platelet aggregation in nanomolar concentration (21 nM), thus showing potential in prevention of thrombus formation as functional food or dietary supplement. Antiplatelet activity was related to antioxidant capacity (r=0.7014, p=0.0352) indicating that prevention of aggregation is not caused by an individual component, but it is rather a result of synergistic effect of polyphenols. The obtained results are preliminary and a more detailed study of the possibility of applying the investigated plant species as supplements for the prevention of the problem of cardiovascular system and platelet aggregation is needed.

Ključne riječi
sage; flavonoids; phenolic acids; platelet aggregation

Hrčak ID: 203495

URI
https://hrcak.srce.hr/203495

[hrvatski]

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