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https://doi.org/10.5562/cca3341

Crystal Structures of the Single PDZ Domains from GRASP65 and their Interaction with the Golgin GM130

Claudia M. Jurk ; Macromolecular Structure and Interaction Laboratory, Max-Delbrück-Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany
Yvette Roske ; Macromolecular Structure and Interaction Laboratory, Max-Delbrück-Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany
Udo Heinemann   ORCID icon orcid.org/0000-0002-8191-3850 ; Macromolecular Structure and Interaction Laboratory, Max-Delbrück-Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany

Puni tekst: engleski, pdf (3 MB) str. 255-264 preuzimanja: 492* citiraj
APA 6th Edition
Jurk, C.M., Roske, Y. i Heinemann, U. (2018). Crystal Structures of the Single PDZ Domains from GRASP65 and their Interaction with the Golgin GM130. Croatica Chemica Acta, 91 (2), 255-264. https://doi.org/10.5562/cca3341
MLA 8th Edition
Jurk, Claudia M., et al. "Crystal Structures of the Single PDZ Domains from GRASP65 and their Interaction with the Golgin GM130." Croatica Chemica Acta, vol. 91, br. 2, 2018, str. 255-264. https://doi.org/10.5562/cca3341. Citirano 08.03.2021.
Chicago 17th Edition
Jurk, Claudia M., Yvette Roske i Udo Heinemann. "Crystal Structures of the Single PDZ Domains from GRASP65 and their Interaction with the Golgin GM130." Croatica Chemica Acta 91, br. 2 (2018): 255-264. https://doi.org/10.5562/cca3341
Harvard
Jurk, C.M., Roske, Y., i Heinemann, U. (2018). 'Crystal Structures of the Single PDZ Domains from GRASP65 and their Interaction with the Golgin GM130', Croatica Chemica Acta, 91(2), str. 255-264. https://doi.org/10.5562/cca3341
Vancouver
Jurk CM, Roske Y, Heinemann U. Crystal Structures of the Single PDZ Domains from GRASP65 and their Interaction with the Golgin GM130. Croatica Chemica Acta [Internet]. 2018 [pristupljeno 08.03.2021.];91(2):255-264. https://doi.org/10.5562/cca3341
IEEE
C.M. Jurk, Y. Roske i U. Heinemann, "Crystal Structures of the Single PDZ Domains from GRASP65 and their Interaction with the Golgin GM130", Croatica Chemica Acta, vol.91, br. 2, str. 255-264, 2018. [Online]. https://doi.org/10.5562/cca3341

Sažetak
Among the major components of the Golgi apparatus are the GRASP family proteins, including GRASP65 on the cis-Golgi side. With its GRASP domain, GRASP65 is involved in Golgi stacking and ribbon formation. Interaction of GRASP65 with the Golgi marker protein GM130 is important for the docking of vesicles to the Golgi membrane. We present here structures of the two individual PDZ domains comprising the GRASP domain in human GRASP65. We use isothermal titration calorimetry to probe the interaction between GRASP65 and GM130. Additionally, we present evidence for the limited sequence conservation of the PDZ fold by describing the PDZ domain structure of the GRASP65 homolog Grh1 from Saccharomyces cerevisiae.

Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License.

Ključne riječi
PDZ domain structure; Golgi stacking; GRASP family; Golgins; Golgi apparatus; yeast homolog of GRASP65; vesicle transport; Grh1

Hrčak ID: 203537

URI
https://hrcak.srce.hr/203537

Posjeta: 621 *