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Is there any Correlation between Red Cell Distribution Width, Mean Platelet Volume Neutrophil Count, Lymphocyte Count, and Psoriasis Area Severity Index in Patients Under Treatment for Psoriasis?

Pelin Ustuner ; Istanbul Medipol University, School of Medicine, Department of Dermatology, Istanbul, Turkey.
Ali Balevi
Oktay Olmuscelik
Mustafa Ozdemir

Puni tekst: engleski, PDF (295 KB) str. 199-199 preuzimanja: 266* citiraj
APA 6th Edition
Ustuner, P., Balevi, A., Olmuscelik, O. i Ozdemir, M. (2018). Is there any Correlation between Red Cell Distribution Width, Mean Platelet Volume Neutrophil Count, Lymphocyte Count, and Psoriasis Area Severity Index in Patients Under Treatment for Psoriasis?. Acta Dermatovenerologica Croatica, 26 (3), 199-199. Preuzeto s https://hrcak.srce.hr/207005
MLA 8th Edition
Ustuner, Pelin, et al. "Is there any Correlation between Red Cell Distribution Width, Mean Platelet Volume Neutrophil Count, Lymphocyte Count, and Psoriasis Area Severity Index in Patients Under Treatment for Psoriasis?." Acta Dermatovenerologica Croatica, vol. 26, br. 3, 2018, str. 199-199. https://hrcak.srce.hr/207005. Citirano 17.10.2021.
Chicago 17th Edition
Ustuner, Pelin, Ali Balevi, Oktay Olmuscelik i Mustafa Ozdemir. "Is there any Correlation between Red Cell Distribution Width, Mean Platelet Volume Neutrophil Count, Lymphocyte Count, and Psoriasis Area Severity Index in Patients Under Treatment for Psoriasis?." Acta Dermatovenerologica Croatica 26, br. 3 (2018): 199-199. https://hrcak.srce.hr/207005
Harvard
Ustuner, P., et al. (2018). 'Is there any Correlation between Red Cell Distribution Width, Mean Platelet Volume Neutrophil Count, Lymphocyte Count, and Psoriasis Area Severity Index in Patients Under Treatment for Psoriasis?', Acta Dermatovenerologica Croatica, 26(3), str. 199-199. Preuzeto s: https://hrcak.srce.hr/207005 (Datum pristupa: 17.10.2021.)
Vancouver
Ustuner P, Balevi A, Olmuscelik O, Ozdemir M. Is there any Correlation between Red Cell Distribution Width, Mean Platelet Volume Neutrophil Count, Lymphocyte Count, and Psoriasis Area Severity Index in Patients Under Treatment for Psoriasis?. Acta Dermatovenerol Croat. [Internet]. 2018 [pristupljeno 17.10.2021.];26(3):199-199. Dostupno na: https://hrcak.srce.hr/207005
IEEE
P. Ustuner, A. Balevi, O. Olmuscelik i M. Ozdemir, "Is there any Correlation between Red Cell Distribution Width, Mean Platelet Volume Neutrophil Count, Lymphocyte Count, and Psoriasis Area Severity Index in Patients Under Treatment for Psoriasis?", Acta Dermatovenerologica Croatica, vol.26, br. 3, str. 199-199, 2018. [Online]. Dostupno na: https://hrcak.srce.hr/207005. [Citirano: 17.10.2021.]

Sažetak

Psoriasis vulgaris is a well-known systemic inflammatory disease accompanied by many cardiac, renal, and metabolic manifestations. In recent years, hematological parameters have been studied in different systemic diseases as markers for inflammation. In this study, we investigated the possible association between the hematological parameters, namely neutrophil-to-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), red cell distribution width (RDW), and Psoriasis Area Severity Index (PASI) scores, in patients under treatment for psoriasis.

Forty-five patients with moderate to severe psoriasis and PASI values of 7 or greater were included in the study. Patients with other inflammatory diseases were excluded. All the patients were treated according to the severity of the disease. Hematological parameters and PASI were examined at baseline and at month 3, 6, 9, and 12.

Twenty-seven patients (60%) were women, and the mean age was 42.2 years. No statistically significant association was found between PASI values and NLR, PLR, or RDW at months 0 and 12. The mean platelet volumes increased only at month 3, and lymphocyte counts increased significantly at all months. However, platelet counts decreased significantly only at month 6, 9, and 12, while RDW decreased significantly only at month 3. All the remaining parameters such as: neutrophils count, lymphocyte count, and erythrocyte sedimentation rate decreased significantly.

The decrease in RDW and the increase in the mean platelet volume accompanied by a decrease in PASI values may represent contributing prognostic hematologic parameters to predict clinical progress and treatment response of patients with moderate-severe psoriasis during the first 3 months of treatment.

 

Ključne riječi
Lymphocyte Count; Mean Platelet Volume; Neutrophils; Psoriasis

Hrčak ID: 207005

URI
https://hrcak.srce.hr/207005

Posjeta: 460 *