Izvorni znanstveni članak
https://doi.org/10.24141/1/4/2/2
The impact of demographic and socio-economic factors on the prevalence of syndromes of autosomal chromosomal anomalies in post-war Bosnia and Herzegovina
Jure Pupić-Bakrač
; Centar urgentne medicine i hitnog bolničkog prijema, Sveučilišna klinička bolnica Mostar, Mostar, Bosna i Hercegovina
Tomica Božić
; Klinika za pedijatriju, Sveučilišna klinička bolnica Mostar, Mostar, Bosna i Hercegovina
Ana Pupić-Bakrač
; Odjel za obiteljsku medicinu, Dom zdravlja Mostar, Mostar, Bosna i Hercegovina
Ivan Lasić
; Centar za medicinsku fiziku i zaštitu od zračenja, Sveučilišna klinička bolnica Mostar, Mostar, Bosna i Hercegovina
Tatjana Barišić
; Klinika za ginekologiju i porodništvo, Sveučilišna klinička bolnica Mostar, Mostar, Bosna i Hercegovina
Sažetak
Introduction: Syndromes of autosomal chromosomal anomalies have a prevalence of 1: 500 in live-born children and are often associated with severe health and social problems. Except for the advanced maternal age at the moment of conception, little is known about the risk factors for their development.
Respondents and Methods: The respondents in this research were 97 children diagnosed with syndromes of autosomal chromosomal anomalies, born from 2000 to 2015, with a place of residence in 3 municipalities of Federation of Bosnia and Herzegovina. A chronologic cohort research has been conducted. The prevalence of syndromes was analyzed with respect to the parents’ place of residence (rural or urban area) and theirs municipality development index.
Results: Of 50,458 live-born children, between 2000 and 2015, syndromes of autosomal chromosomal anomalies were detected in 97 (0.19%) newborns. Out of the total number of live-born children, 21116 were born in the urban area, and 29342 in the rural area. In the same period in the urban area, there were 30 (0.14%) and in rural 67 (0.23%) affected. The prevalence of syndromes of autosomal chromosomal anomalies in 11 different municipalities, classified by the development index, in the period from 2007 to 2015, was 0.19% in the group of municipalities with the development index > 100, and
0,30% in the group with <100.
Conclusion: Analyzing the prevalence of syndromes of autosomal chromosomal anomalies it has been established that the parents’ place of residence in the rural area of the Federation of Bosnia and Herzegovina is a risk factor for their occurrence.
Ključne riječi
chromosome aberrations; syndrome; risk factors
Hrčak ID:
207635
URI
Datum izdavanja:
30.10.2018.
Posjeta: 1.221 *