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https://doi.org/10.20471/acc.2018.57.s1.05

Diagnostic Value of Cognitive-Registration Multiparametric Magnetic Resonance Guided Biopsy for the Detection of Prostate Cancer after Initial Negative Biopsy

Igor Tomašković orcid id orcid.org/0000-0003-4182-9707 ; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Faculty of Medicine, Josip Juraj Strossmayer University, Osijek, Croatia; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Ivan Pezelj ; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Karolina Bolanča Čulo ; Department of Radiology, Sestre milosrdnice University Hospital Center
Luka Novosel ; Department of Radiology, Sestre milosrdnice University Hospital Center
Sven Nikles ; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Miroslav Tomić ; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Ante Reljić ; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Josip Katušić ; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Matej Knežević ; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Matea Pirša ; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Božo Kruslin ; Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Center
Monika Ulamec ; Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Center
Boris Ružić ; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia


Puni tekst: engleski pdf 745 Kb

str. 40-45

preuzimanja: 441

citiraj


Sažetak

The aim of this prospective clinical study was to determine the detection rate of prostate cancers by multiparametric magnetic resonance and transrectal ultrasound (mpMRI-TRUS) cognitive fusion biopsies in patients with a previously negative TRUS-guided biopsy. Between 1 October 2016 and 1 July 2017, in 101 consecutive patients with elevated antigen (PSA) and/or positive digital rectal examination and after a negative first TRUS biopsy, a second, repeated prostate biopsy was performed. In 24 patients, cognitive fusion mpMRI-TRUS biopsy of the prostate with 8-10 system cores and 1-3 target biopsies was performed, in line with the European Association of Urology guidelines. In 77 patients, only a classic, repeated TRUS guided biopsy was performed. In patients with mpMRI, the detection rate according to PIRADS-v2 reporting system was: PIRADS 1, n = 0; PIRADS 2, n = 0; PIRADS 3, n = 0; PIRADS 4, n = 6/8 (75%); and PIRADS 5, n = 2/3 (67%). In the group of patients with MR-TRUS cognitive fusion biopsy, the prostate cancer detection rate was 8/24 (33%), while in the control group the detection rate was 12/77 (16%), which was statistically significant (t test, p = 0.037, CI 95% is 0.01 to 0.37). Patients with PIRADS ≤ 3 (54%) could have avoided the biopsy.

Ključne riječi

Prostate cancer; Multiparametric magnetic resonance; Biopsy

Hrčak ID:

207888

URI

https://hrcak.srce.hr/207888

Datum izdavanja:

1.10.2018.

Podaci na drugim jezicima: hrvatski

Posjeta: 5.648 *