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A nanodiamond for structural biomimetic scaffolds

Raffaella Aversa
Relly Victoria Virgil Petrescu
Antonio Apicella   ORCID icon
Florian Ion Tiberiu Petrescu   ORCID icon ; Bucharest Polytechnic University

Puni tekst: engleski, pdf (343 KB) str. 81-89 preuzimanja: 134* citiraj
APA 6th Edition
Aversa, R., Virgil Petrescu, R.V., Apicella, A. i Tiberiu Petrescu, F.I. (2019). A nanodiamond for structural biomimetic scaffolds. Engineering Review, 39 (1), 81-89.
MLA 8th Edition
Aversa, Raffaella, et al. "A nanodiamond for structural biomimetic scaffolds." Engineering Review, vol. 39, br. 1, 2019, str. 81-89. Citirano 07.04.2020.
Chicago 17th Edition
Aversa, Raffaella, Relly Victoria Virgil Petrescu, Antonio Apicella i Florian Ion Tiberiu Petrescu. "A nanodiamond for structural biomimetic scaffolds." Engineering Review 39, br. 1 (2019): 81-89.
Aversa, R., et al. (2019). 'A nanodiamond for structural biomimetic scaffolds', Engineering Review, 39(1), str. 81-89.
Aversa R, Virgil Petrescu RV, Apicella A, Tiberiu Petrescu FI. A nanodiamond for structural biomimetic scaffolds. Engineering Review [Internet]. 2019 [pristupljeno 07.04.2020.];39(1):81-89.
R. Aversa, R.V. Virgil Petrescu, A. Apicella i F.I. Tiberiu Petrescu, "A nanodiamond for structural biomimetic scaffolds", Engineering Review, vol.39, br. 1, str. 81-89, 2019. [Online].

Bio-mechanically active scaffolds for tissue engineering combining hydrophilic polymeric matrix and nano-diamond fillers properties are presented and discussed in this paper. The resulting scaffolding materials revealed remarkable mechanical and biological properties to be exploited in advanced biomedical applications. The novel hybrid material is based on 2 and 5 volume % of detonation nano-diamond particles in a hydrophilic poly-(hydroxyl-ethylmethacrylate) matrix. According to its mechanical and biological properties, the nanocomposite shows a hybrid nature. The base analytical procedures for the preparation of the hybrid nanocomposites and some preliminary mechanical characteristics are presented. The proposed hybrid system has been considered for potential biomimetic, osteoconductive and osteoinductive scaffolds application in bio-mechanically active bone scaffolds for osteoblast and stem cell differentiation and growth. These more rigid hybrid nano-composites are predicted to possess improved mechanical strength overcoming the mechanical weaknesses of traditional hydrogels clinically utilized for bone regeneration.

Ključne riječi
hybrid nano-composites; biomaterials; bioactive scaffolds; bioengineering; biomedical

Hrčak ID: 215365


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