Kratko priopćenje
https://doi.org/10.5513/JCEA01/20.1.2412
Elevated haplotypes frequencies reveal similarities for selection signatures in Western and Russian Simmental populations
Gabor Meszaros
; University of Natural Resources and Life Sciences, Vienna, Division of Livestock Sciences, Gregor Mendel Str.33, A-1180 Vienna, Austria
Margaret Fornara
; Federal Science Center for Animal Husbandry named after Academy Member L.K. Ernst, Dubrovitsy 60, 142132 Podolsk, Russia
Henry Reyer
; Leibniz Institute for Farm Animal Biology, Institute of Genome Biology, Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Mecklenburg-Vorpommern, Germany
Klaus Wimmers
; Leibniz Institute for Farm Animal Biology, Institute of Genome Biology, Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Mecklenburg-Vorpommern, Germany
Johann Solkner
; University of Natural Resources and Life Sciences, Vienna, Division of Livestock Sciences, Gregor Mendel Str.33, A-1180 Vienna, Austria
Gottfried Brem
; University of Veterinary Medicine, Institute of Animal Breeding and Genetics, Veterinärplatz 1, A-1210 Vienna, Austria
Alexander Sermyagin
; Federal Science Center for Animal Husbandry named after Academy Member L.K. Ernst, Dubrovitsy 60, 142132 Podolsk, Russia
Natalia Zinovieva
; Federal Science Center for Animal Husbandry named after Academy Member L.K. Ernst, Dubrovitsy 60, 142132 Podolsk, Russia
Sažetak
This paper shows a straightforward, but surprisingly effective approach to detect genomic regions of importance, illustrated on two Simmental cattle populations. Medium density genomic data of 42 German/Austrian (denoted as “Western“) and 38 Russian Simmental cattle were used to identify the most frequent haplotypes within the two populations. The haplotypes were defined as non-overlapping segments of ten single nucleotide polymorphisms (SNP). The phasing was done with the SHAPEIT software, with a follow up analysis of haplotypes using the GHap package. Despite the low sample size a number of high frequency haplotypes could be identified across the whole genome. The identified genes residing directly in these high frequency haplotypes were extremely relevant for the dual purpose Simmental cattle. A large part of these genes influenced growth rate and carcass traits, others were relevant for the milk production. A smaller proportion was connected to the reproduction, immune system and cellular processes, with indirect influence on production traits.
Ključne riječi
cattle; genome architecture; haplotype analysis; Simmental
Hrčak ID:
218051
URI
Datum izdavanja:
19.3.2019.
Posjeta: 1.027 *