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Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia

Branislav Lekić
Mirjana Gajić-Veljić
Branka Bonači-Nikolić
Miloš Nikolić ; Department of DermatovenereologyFaculty of Medicine, University of BelgradePasterova 211000 BelgradeSerbia

Fulltext: english, PDF (184 KB) pages 28-28 downloads: 189* cite
APA 6th Edition
Lekić, B., Gajić-Veljić, M., Bonači-Nikolić, B. & Nikolić, M. (2019). Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia. Acta Dermatovenerologica Croatica, 27 (1), 28-28. Retrieved from https://hrcak.srce.hr/219586
MLA 8th Edition
Lekić, Branislav, et al. "Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia." Acta Dermatovenerologica Croatica, vol. 27, no. 1, 2019, pp. 28-28. https://hrcak.srce.hr/219586. Accessed 2 Dec. 2021.
Chicago 17th Edition
Lekić, Branislav, Mirjana Gajić-Veljić, Branka Bonači-Nikolić and Miloš Nikolić. "Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia." Acta Dermatovenerologica Croatica 27, no. 1 (2019): 28-28. https://hrcak.srce.hr/219586
Harvard
Lekić, B., et al. (2019). 'Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia', Acta Dermatovenerologica Croatica, 27(1), pp. 28-28. Available at: https://hrcak.srce.hr/219586 (Accessed 02 December 2021)
Vancouver
Lekić B, Gajić-Veljić M, Bonači-Nikolić B, Nikolić M. Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia. Acta Dermatovenerol Croat. [Internet]. 2019 [cited 2021 December 02];27(1):28-28. Available from: https://hrcak.srce.hr/219586
IEEE
B. Lekić, M. Gajić-Veljić, B. Bonači-Nikolić and M. Nikolić, "Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia", Acta Dermatovenerologica Croatica, vol.27, no. 1, pp. 28-28, 2019. [Online]. Available: https://hrcak.srce.hr/219586. [Accessed: 02 December 2021]

Abstracts

Cutaneous necrotizing eosinophilic vasculitis (CNEV) is a rare type of vasculitis. Eosinophilic vasculitis is a necrotizing vasculitis with eosinophilic vascular infiltration, in which eosinophils mediate vascular damage in the disease process. We present a case of an 18-year-old girl who developed palpable purpura and hemorrhagic bullae over the lower extremities associated with itching, 7 days after the commencement of penicillin therapy. Plasma cryofibrinogen was positive. Histopathology showed an infiltration of eosinophils within and around the vessel walls and a complete absence of nuclear dust and neutrophils. Oral prednisone at 1 mg/kg induced remission in 2 weeks; the prednisone dose was tapered and discontinued after 2.5 months. There was no evidence of recurrence after 37 months of follow-up. Our patient represents a rare case of drug/penicillin-induced CNEV associated with cryofibrinogenemia, without systemic organ involvement.

, and histopathological features of the lesion. Moreover, the possible complications of surgical approaches, namely healing defects, failure of skin grafts, and wound infection, should be considered. In this review we discuss the management of BCC localized on the face and scalp, according to the currently available treatment options.

 

 

Hrčak ID: 219586

URI
https://hrcak.srce.hr/219586

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