hrcak mascot   Srce   HID

Sažetak sa skupa

The effect of pentadecapeptide BPC 157 on high-fat diet induced hypertension in rat

Vilim Dretar ; School of Medicine University of Zagreb, Department of Pharmacology
Filip Radevski ; School of Medicine University of Zagreb, Department of Pharmacology
Pavla Peraić ; School of Medicine University of Zagreb, Department of Pharmacology
Josh Fry ; School of Medicine University of Zagreb, Department of Pharmacology
Marko Belamarić ; School of Medicine University of Zagreb, Department of Pharmacology
Marko Antunović ; School of Medicine University of Zagreb, Department of Pharmacology
Ivan Krezić ; School of Medicine University of Zagreb, Department of Pharmacology

Puni tekst: engleski, pdf (67 KB) str. 0-0 preuzimanja: 4* citiraj
APA 6th Edition
Dretar, V., Radevski, F., Peraić, P., Fry, J., Belamarić, M., Antunović, M. i Krezić, I. (2019). The effect of pentadecapeptide BPC 157 on high-fat diet induced hypertension in rat. Liječnički vjesnik, 141 (suppl.1), 0-0. Preuzeto s https://hrcak.srce.hr/221663
MLA 8th Edition
Dretar, Vilim, et al. "The effect of pentadecapeptide BPC 157 on high-fat diet induced hypertension in rat." Liječnički vjesnik, vol. 141, br. suppl.1, 2019, str. 0-0. https://hrcak.srce.hr/221663. Citirano 15.12.2019.
Chicago 17th Edition
Dretar, Vilim, Filip Radevski, Pavla Peraić, Josh Fry, Marko Belamarić, Marko Antunović i Ivan Krezić. "The effect of pentadecapeptide BPC 157 on high-fat diet induced hypertension in rat." Liječnički vjesnik 141, br. suppl.1 (2019): 0-0. https://hrcak.srce.hr/221663
Harvard
Dretar, V., et al. (2019). 'The effect of pentadecapeptide BPC 157 on high-fat diet induced hypertension in rat', Liječnički vjesnik, 141(suppl.1), str. 0-0. Preuzeto s: https://hrcak.srce.hr/221663 (Datum pristupa: 15.12.2019.)
Vancouver
Dretar V, Radevski F, Peraić P, Fry J, Belamarić M, Antunović M i sur. The effect of pentadecapeptide BPC 157 on high-fat diet induced hypertension in rat. Liječnički vjesnik [Internet]. 2019 [pristupljeno 15.12.2019.];141(suppl.1):0-0. Dostupno na: https://hrcak.srce.hr/221663
IEEE
V. Dretar, et al., "The effect of pentadecapeptide BPC 157 on high-fat diet induced hypertension in rat", Liječnički vjesnik, vol.141, br. suppl.1, str. 0-0, 2019. [Online]. Dostupno na: https://hrcak.srce.hr/221663. [Citirano: 15.12.2019.]

Sažetak
Hyperlipidaemia, hypercholesterolaemia and hypertriglyceridaemia are known as factors that increas blood pressure and risk of cardiovascular complications. We wanted to examine effects of pentadecapeptide BPC 157 on high-fat diet induced hypertension in rats. 4 Male Winstar Albino rats (240g) 4 months old, were used in this study. 2 rats per each group were fed with fat (white bacon) for 4 weeks. Control group was given water p.o. ad libitum while BPC group was given (10ng/kg) of pentadecapeptide BPC 157 per liter solution p.o. ad libitum. Blood pressure was measured using noninvasive tail cuff method every day for 4 weeks period. Systolic blood pressure increased in both groups but increase in control groups was significantly higher then in BPC 157 threated group (CON day 0. = 158 mmHg, BPC day 0. = 155 mmHg; CON day 25. = 205 mmHg, BPC day 25. = 165 mmHg) .Drop of blood pressure in first few days can be attributed to adapting on the new food that was given to rats. Feeding rats with a high-fat diet is known to produce changes of which one of the consequence is increased blood pressure or hypertension. We proved that pentadecapeptide BPC 157 decreases systolic blood pressure induced by fat diet.

Ključne riječi
BPC 157, high-fat diet, hypertension, rats

Hrčak ID: 221663

URI
https://hrcak.srce.hr/221663

Posjeta: 16 *