Medicus, Vol. 12 No. 2_Spolne bolesti, 2003.
Pregledni rad
Treatment of Urogenital Infections in Pregnancy
Igor Francetić
Sažetak
Treatment of urogenital infections and sexually
transmitted diseases in pregnancy is complicated by the rejection
of a pregnant woman to undergo treatment due to fear of
possible damage to the fetus. The consequences of nontreatment
or inappropriate treatment are much worse for the fetus
than potential damage from drugs used in therapy. For the successful
therapy and protection of the fetus it is important to start
treatment early, i.e. on time. For the treatment of C. trachomatis
infection one dose of 1000 mg azithromycin, amoxicillin
3x500 mg during 7 days or erythromycin 4x500 mg through 7
days or 4x250 mg through 14 days can be applied. Gonorrhoea
in pregnancy is treated with one dose of 125 mg ceftriaxone
i.m., 500 mg cefotaxime i.m. or 2.0 mg spectinomycin i.m.
Syphilis is being treated with penicillin, while therapeutic schedule
depends on the stage of the disease. Genital herpes is an
incurable viral infection of recurrent type. The first clinical
episode of genital herpes during pregnancy can be treated with
acyclovir 5x400 mg daily through 7-10 days. In the case of life
threatening herpes simplex viral infection in a pregnant woman,
i.v. administration of acyclovir is indicated. A pregnant woman
with the confirmed U. urealyticum and/or M. hominis should
be treated. Trichomoniasis in pregnancy is treated with metronidazole,
bacterial vaginosis with metronidazole or clindamycin,
and vulvovaginal candidiasis with local application of azole. In
pregnant women both asymptomatic and symptomatic urinary
infections must be treated. Applied are betalactamic antibiotics
and nitrofurantoins. Screening for bacteriuria in the first
trimester is justified, as well as for the C. trachomatis infection.
Ključne riječi
urogenital infections; sexually transmitted diseases; treatment; pregnancy
Hrčak ID:
20576
URI
Datum izdavanja:
7.10.2003.
Posjeta: 4.954 *